| 货号 | 产品名称 | 蛋白编码 | 图片 |
|---|---|---|---|
| ALP6583 |
Cynomolgus B7-1/CD80 Protein, Cynomolgus, HEK293, C-6His 重组蛋白Cynomolgus B7-1/CD80 Protein, Cynomolgus, HEK293, C-6His |
G7NXN7 (V35-N242) |
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| CD80 是一种癌症免疫的共刺激细胞因子，通过结合 CD28 或 CTLA-4 而激活。CD80 低表达时会发生肿瘤免疫逃逸。CD80 受 TP53 诱导表达增加，会刺激抗肿瘤免疫反应。 | |||
| ALP6589 | P10747-1/ Q0PDN3 /Q0PDN4 (N19-P152) |
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| CD28 蛋白对于 T 细胞激活、增强增殖、细胞因子产生和存活至关重要。当与 TCR/CD3 和 CD40L 连接时，CD28 促进 IL4 和 IL10 的产生，从而调节免疫反应。 | |||
| ALP8136 | O75144 -1 (D19-S258) |
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| Adamas-life ® B7-H2, also known as B7-related protein (B7RP1), ICOS Ligand, and CD275, is an approximately 60 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. B7-H2 is a ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. | |||
| ALP8144 | O75144 -1 (D19-S258) |
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| B7-H2, also known as B7-related protein (B7RP1), ICOS Ligand, and CD275, is an approximately 60 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. B7-H2 is a ligand for the T- cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. | |||
| ALP8140 | Q68D85 (D25-S262) |
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| B7-H6 is a glycosylated member of the B7 family of immune co ‑ stimulatory proteins. which is a ligand for the NK cell activating receptor NKp30, was targeted to create a CAR that targets multiple tumor types. B7H6 is expressed on various primary human tumors, including leukemia, lymphoma and gastrointestinal stromal tumors, but it is not constitutively expressed on normal tissues. | |||
| ALP8126 |
Cynomolgus B7-H2/ICOSLG Protein,Cynomolgus,C-His,Expi293 重组蛋白Cynomolgus B7-H2/ICOSLG Protein,Cynomolgus,C-His,Expi293 |
XP_005548617.1 (D19-T256) |
|
| B7-H2, also known as B7-related protein (B7RP1), ICOS Ligand, and CD275, is an approximately 60 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. B7-H2 is a ligand for the T- cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. | |||
| ALP8133 | Q68D85 (D25-S262) |
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| B7-H6 is a glycosylated member of the B7 family of immune co ‑ stimulatory proteins. which is a ligand for the NK cell activating receptor NKp30, was targeted to create a CAR that targets multiple tumor types. B7H6 is expressed on various primary human tumors, including leukemia, lymphoma and gastrointestinal stromal tumors, but it is not constitutively expressed on normal tissues. | |||
