属于免疫球蛋白超家族，主要表达于乳腺和免疫细胞，参与脂质代谢调控及T细胞活化调节，尤其在哺乳期乳腺免疫中发挥关键作用。
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| 产品号 | 产品名称 | 蛋白编码 | 图片 |
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| ALP8156 |
Cynomolgus BTN3A1/CD277 Protein,Cynomolgus,C-His-Avi,Expi293 重组蛋白Cynomolgus BTN3A1/CD277 Protein,Cynomolgus,C-His-Avi,Expi293 |
A0A330KWZ1 (Q1-W219) |
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| The three butyrophilin BTN3A molecules, BTN3A1, BTN3A2, and BTN3A3, are members of the B7/butyrophilin-like group of Ig superfamily receptors, which modulate the function of T cells. BTN3A1 controls activation of human Vγ9/Vδ2 T cells by direct or indirect presentation of self and nonself phosphoantigens (pAg). | |||
| ALP8157 | O00481 -1 (Q30-G254) |
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| The three butyrophilin BTN3A molecules, BTN3A1, BTN3A2, and BTN3A3, are members of the B7/butyrophilin-like group of Ig superfamily receptors, which modulate the function of T cells. BTN3A1 controls activation of human Vγ9/Vδ2 T cells by direct or indirect presentation of self and nonself phosphoantigens (pAg). | |||
| ALP8158 | Q13410 (A27-R242) |
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| Butyrophilin 1A1 (BTN1A1) is one of the membrane proteins that surrounds LD, BTN1A1 plays an important role in regulating LD synthesis via a mechanism involving membrane phospholipid composition. | |||
| ALP8159 | O00481 -1 (Q30-G254) |
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| The three butyrophilin BTN3A molecules, BTN3A1, BTN3A2, and BTN3A3, are members of the B7/butyrophilin-like group of Ig superfamily receptors, which modulate the function of T cells. BTN3A1 controls activation of human Vγ9/Vδ2 T cells by direct or indirect presentation of self and nonself phosphoantigens (pAg). | |||
| ALP8160 |
Human BTN1A1/Butyrophilin Protein,Human,C-His-Avi,Expi293 重组蛋白Human BTN1A1/Butyrophilin Protein,Human,C-His-Avi,Expi293 |
Q13410 (A27-R242) |
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| Butyrophilin 1A1 (BTN1A1) is one of the membrane proteins that surrounds LD, BTN1A1 plays an important role in regulating LD synthesis via a mechanism involving membrane phospholipid composition. | |||
| ALP8148 | P78410 -1 (Q30-W248) |
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| BTN3A2/BT3.2 butyrophilin mRNA expression by tumoral cells was previously identified as a prognostic factor in a small cohort of high grade serous epithelial ovarian cancer (HG-EOC).In conclusion, BT3.2 protein is a potential prognostic biomarker for the identification of HG-EOC patients with better outcome. In contrast, high CD206 /CD68 expression is associated with high risk of disease progression. | |||
| ALP9256 | O00478-1(Gln30-Trp248) |
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| The butyrophilin (BTN) family has many members with diverse functions related to immunomodulation, initiation and progression of tumors. BTN3A3 belongs to the BTN family, and exploring its expression and correlation with the prognosis of non-small cell lung cancer (NSCLC) patients has great clinical significance.The expression of BTN3A3 in NSCLC tissues was significantly lower than in adjacent tissues, and patients with low expression of BTN3A3 had late clinical stages and lower degree of tumor differentiation. | |||
| ALP22733 | Q6UX41-1(Q18-K238) |
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| BTNL8 protein potentially stimulates the primary immune response by affecting sub-optimally stimulated T-cells through the TCR/CD3 complex. It promotes T-cell proliferation and enhances cytokine production. | |||
| ALP22553 | Q8WVV5(Q33-V237) |
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| BTN2A2 is a member of butyrophilin family. | |||
| ALP22632 | Q7KYR7-2(Q29-A248) |
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| BTN2A1 is a member of butyrophilin family. | |||
| ALP22635 | O00481-1(Q30-G254) |
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| BTN3A1/CD277 Protein, functioning as a homodimer, regulates activated T-cell proliferation, controls cytokine release, and mediates T-cell response to cells with elevated phosphorylated metabolites, such as isopentenyl pyrophosphate, contributing to T-cell activation and the adaptive immune response. | |||
| ALP22662 | A2CG22(K29-W249) |
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| BTNL6 Protein, part of the immunoglobulin superfamily in the BTN/MOG family, is associated with immune responses and cellular recognition. Its membership suggests involvement in diverse immunological processes, potentially contributing to intricate immune regulation. Further exploration is needed to understand BTNL6's specific functions within the broader immunoglobulin superfamily context and its role in modulating immune responses. | |||
| ALP22597 | O70355(D27-S452) |
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| BTNL2 is a member of butyrophilin-like proteins. | |||
| ALP22604 | Q6UXG8-1(L48-S160) |
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| BTNL9 is a member of BTNL family. | |||
| ALP22639 | A4QPC6-1(Q30-S244) |
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| BTN2A2 protein inhibits CD4 and CD8 T-cell proliferation activated by anti-CD3 antibodies. It regulates T-cell metabolism, suppressing IL2 and IFNG cytokine secretion. BTN2A2 plays a pivotal role in immune response modulation, maintaining immune homeostasis by limiting T-cell activation and effector functions. | |||
