一种免疫共刺激分子，属于B7家族，在多种肿瘤细胞表面高表达，参与调节T细胞免疫应答，成为癌症免疫治疗的重要靶点。
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| 产品号 | 产品名称 | 蛋白编码 | 图片 |
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| ALP8129 | Q5ZPR3 -2 (L29-P245) |
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| Adamas-life ® B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig ‑ B7 ‑ H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. | |||
| ALP8137 | Q5ZPR3 -2 (L29-P245) |
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| B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig ‑ B7 ‑ H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. | |||
| ALP22447 | XP_015308534.1(L29-E465) |
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| CD276/B7-H3 protein can regulate T cell-mediated immune responses and act as a protective factor for tumor cells by inhibiting natural killer-mediated cell lysis . It also functions as a neuroblastoma cell marker, plays a role in acute and chronic transplant rejection, and modulates lymphocyte activity at mucosal surfaces. | |||
| ALP22315 |
Recombinant Biotinylated CD276/B7-H3 Protein,Human,HEK293,C-Fc-Avi |
Q5ZPR3-2(L29-P245) |
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| CD276/B7-H3 protein can regulate T cell-mediated immune responses and act as a protective factor for tumor cells by inhibiting natural killer-mediated cell lysis . It also functions as a neuroblastoma cell marker, plays a role in acute and chronic transplant rejection, and modulates lymphocyte activity at mucosal surfaces. | |||
| ALP22339 |
Recombinant FITC-Labeled CD276/B7-H3 4Ig/B7-H3b Protein,Human,HEK293,Fc 重组蛋白FITC-Labeled CD276/B7-H3 4Ig/B7-H3b Protein,Human,HEK293,Fc |
Q5ZPR3-1(G27-T461) |
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| CD276/B7-H3 protein can regulate T cell-mediated immune responses and act as a protective factor for tumor cells by inhibiting natural killer-mediated cell lysis . It also functions as a neuroblastoma cell marker, plays a role in acute and chronic transplant rejection, and modulates lymphocyte activity at mucosal surfaces. | |||
| ALP22156 |
Recombinant CD276/B7-H3 4Ig/B7-H3b Protein,Human,HEK293,C-His |
Q5ZPR3-1(L29-T461) |
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| CD276/B7-H3 protein can regulate T cell-mediated immune responses and act as a protective factor for tumor cells by inhibiting natural killer-mediated cell lysis . It also functions as a neuroblastoma cell marker, plays a role in acute and chronic transplant rejection, and modulates lymphocyte activity at mucosal surfaces. | |||
| ALP22419 | XP_015308534.1(L29-E465) |
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| CD276/B7-H3 protein can regulate T cell-mediated immune responses and act as a protective factor for tumor cells by inhibiting natural killer-mediated cell lysis . It also functions as a neuroblastoma cell marker, plays a role in acute and chronic transplant rejection, and modulates lymphocyte activity at mucosal surfaces. | |||
