一种在肝癌细胞中高表达的癌胚蛋白，参与细胞增殖与分化调控，常作为肝癌诊断和免疫治疗的靶点。
| 产品号 | 产品名称 | 蛋白编码 | 图片 |
|---|---|---|---|
| ALP22306 |
Recombinant Glypican-3/GPC3 Protein,Human S359F,HEK293,C-His |
P51654-1(Q25-H559, S359F) |
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| The Glypican-3 (GPC3) protein is a cell surface proteoglycan that plays complex regulatory roles in key signaling pathways critical to developmental processes. Through its GPI anchoring, GPC3 negatively regulates the Hedgehog signaling pathway by competing with the Hedgehog receptor PTC1 for binding to Hedgehog protein, leading to complex internalization and subsequent lysosomal degradation. | |||
| ALP22336 |
Recombinant PE-labeled Glypican-3/GPC3 Protein,Human,HEK293,His |
P51654-1(Q25-H559) |
|
| The Glypican-3 (GPC3) protein is a cell surface proteoglycan that plays complex regulatory roles in key signaling pathways critical to developmental processes. Through its GPI anchoring, GPC3 negatively regulates the Hedgehog signaling pathway by competing with the Hedgehog receptor PTC1 for binding to Hedgehog protein, leading to complex internalization and subsequent lysosomal degradation. | |||
| ALP22451 | P51654-1/NP_004475.1(Q25-S550, S495A) |
|
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| The Glypican-3 (GPC3) protein is a cell surface proteoglycan that plays complex regulatory roles in key signaling pathways critical to developmental processes. Through its GPI anchoring, GPC3 negatively regulates the Hedgehog signaling pathway by competing with the Hedgehog receptor PTC1 for binding to Hedgehog protein, leading to complex internalization and subsequent lysosomal degradation. | |||
| ALP22711 |
Recombinant Biotinylated Glypican-3/GPC3 Protein,Human,HEK293,C-His |
P51654-1(M1-H559) |
|
| The Glypican-3 (GPC3) protein is a cell surface proteoglycan that plays complex regulatory roles in key signaling pathways critical to developmental processes. Through its GPI anchoring, GPC3 negatively regulates the Hedgehog signaling pathway by competing with the Hedgehog receptor PTC1 for binding to Hedgehog protein, leading to complex internalization and subsequent lysosomal degradation. | |||
| ALP22716 | P51654-1(Q25-H559) |
|
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| The Glypican-3 (GPC3) protein is a cell surface proteoglycan that plays complex regulatory roles in key signaling pathways critical to developmental processes. Through its GPI anchoring, GPC3 negatively regulates the Hedgehog signaling pathway by competing with the Hedgehog receptor PTC1 for binding to Hedgehog protein, leading to complex internalization and subsequent lysosomal degradation. | |||
| ALP22483 | Q8CFZ4(Q25-M557) |
|
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| GPC3 is a cell surface proteoglycan that regulates Hedgehog and Wnt signaling. | |||
| ALP22585 | P51654-1(Q25-H559) |
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| The Glypican-3 (GPC3) protein is a cell surface proteoglycan that plays complex regulatory roles in key signaling pathways critical to developmental processes. Through its GPI anchoring, GPC3 negatively regulates the Hedgehog signaling pathway by competing with the Hedgehog receptor PTC1 for binding to Hedgehog protein, leading to complex internalization and subsequent lysosomal degradation. | |||
