一种受体酪氨酸激酶,与肝细胞生长因子结合后激活信号通路,调控细胞增殖、迁移和形态发生,在胚胎发育和癌症转移中起关键作用。
| 产品号 | 产品名称 | 蛋白编码 | 图片 |
|---|---|---|---|
| ALP22411 | P08581-1(E25-T932) |
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| The HGFR protein is a receptor tyrosine kinase that transduces signals by binding to hepatocyte growth factor/HGF ligand. It regulates proliferation, scattering, morphogenesis, and cell survival. | |||
| ALP22452 |
Recombinant HGFR Protein,Cynomolgus/Rhesus Macaque,HEK293,Tag Free |
XP_005550635.4(E44-T951) |
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| HGFR Protein, a receptor tyrosine kinase, transduces signals by binding hepatocyte growth factor/HGF ligand. It regulates proliferation, scattering, morphogenesis, and cell survival. Upon ligand binding, HGFR undergoes autophosphorylation, creating docking sites for downstream molecules like PI3K , PLCG1, SRC , GRB2, STAT3 , or GAB1, activating RAS-ERK, PI3K-AKT, and PLCgamma-PKC cascades. | |||
| ALP22453 | Q2IBC7(E25-N932) |
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| HGFR Protein is a receptor tyrosine kinase that acts as a signal transducer of the extracellular matrix by binding to hepatocyte growth factor /HGF ligands. HGFR Protein participate in the activation of RAS-ERK, PI3 kinase-AKT, and PLCgamma-PKC signaling pathways. HGFR Protein is essential for embryonic development, organogenesis, and wound healing. | |||
| ALP22310 | P08581-1(E25-T932) |
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| The HGFR protein is a receptor tyrosine kinase that transduces signals by binding to hepatocyte growth factor/HGF ligand. It regulates proliferation, scattering, morphogenesis, and cell survival. | |||
| ALP22373 | Q75ZY9(E25-L935) |
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| The HGFR protein is a receptor tyrosine kinase that transduces signals by binding to hepatocyte growth factor/HGF. It regulates proliferation, scattering, morphogenesis, and cell survival. | |||
| ALP22374 | EDL13881.1(E25-N929) |
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| HGFR Protein, a receptor tyrosine kinase, transduces signals by binding hepatocyte growth factor/HGF ligand. It regulates proliferation, scattering, morphogenesis, and cell survival. Upon ligand binding, HGFR undergoes autophosphorylation, creating docking sites for downstream molecules like PI3K , PLCG1, SRC , GRB2, STAT3 , or GAB1, activating RAS-ERK, PI3K-AKT, and PLCgamma-PKC cascades. | |||
| ALP22375 | P08581-1(E25-G519) |
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| The HGFR protein is a receptor tyrosine kinase that transduces signals by binding to hepatocyte growth factor/HGF ligand. It regulates proliferation, scattering, morphogenesis, and cell survival. | |||