受体酪氨酸激酶样孤儿受体1,参与细胞增殖、分化及迁移,在胚胎发育和多种癌症中异常表达,是潜在治疗靶点。
| 产品号 | 产品名称 | 蛋白编码 | 图片 |
|---|---|---|---|
| ALP22441 | D3ZZ97/EDL97819.1(Q30-E403) |
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| ROR1 protein is an important member of the Tyr protein kinase family in the protein kinase superfamily and plays a key role as a tyrosine kinase in cell signaling and regulation. Its classification emphasizes its importance in phosphorylation events and shares conserved features with related kinases. | |||
| ALP22575 | F1PIX7(A22-E477) |
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| ROR1 protein is an important member of the Tyr protein kinase family in the protein kinase superfamily and plays a key role as a tyrosine kinase in cell signaling and regulation. Its classification emphasizes its importance in phosphorylation events and shares conserved features with related kinases. | |||
| ALP22370 |
Recombinant Biotinylated ROR1 Protein,Human,HEK293,C-His-Avi |
Q01973-1(Q30-E403) |
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| ROR1 protein's minimal kinase activity in vitro suggests an improbable role as a tyrosine kinase in vivo. It serves as a receptor for WNT5A, activating NFkB signaling and potentially inhibiting WNT3A signaling. Notably, ROR1 plays a vital role in the inner ear, facilitating innervation of auditory hair cells by spiral ganglion neurons. | |||