叶酸受体α,一种高亲和力结合叶酸的膜蛋白,在多种肿瘤中过表达,是靶向治疗和诊断的重要标志物。
| 产品号 | 产品名称 | 蛋白编码 | 图片 |
|---|---|---|---|
| ALP22524 | G3V8M6(T25-M231) |
|
|
| The FOLR1 protein is a member of the folate receptor family. Folate receptors are cell surface proteins that bind folate (vitamin B9) and transport it into cells. | |||
| ALP22526 | XP_851993.1(R25-M228) |
|
|
| FOLR1 is a folic acid receptor that binds to folic acid and reductive folic acid derivatives and promotes the entry of 5-methyltetrahydrofolate and folate analogs into the cell interior. FOLR1 enhances the stability and nuclear translocation of β-catenin through the EGFR/AKT/GSK3β axis, thereby promoting the proliferation and migration of laryngeal squamous cell carcinoma (LSCC). | |||
| ALP22316 | P15328(R25-S234) |
|
|
| The FOLR1 protein is an important mediator of folate uptake, binding to folate and promoting the delivery of 5-methyltetrahydrofolate into cells. Studies show high affinity at neutral pH. | |||
| ALP22718 | G3V8M6/NP_598211.1(A20-M231) |
|
|
| The FOLR1 protein is a member of the folate receptor family. Folate receptors are cell surface proteins that bind folate (vitamin B9) and transport it into cells. | |||