一种表达于自然杀伤细胞和部分T细胞表面的免疫受体,参与细胞黏附与激活,调控抗肿瘤和抗病毒免疫应答。
| 产品号 | 产品名称 | 蛋白编码 | 图片 |
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| ALP22443 | Q9NQ25-1(S23-M226) |
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| The CRACC/SLAMF7 protein is an autoligand receptor in the SLAM family that complexly regulates immune cell activation and differentiation through finely regulated interactions. Isoform 1 mediates NK cell activation through an SH2D1A-independent ERK-mediated pathway and positively regulates NK cell function dependent on phosphorylated SH2D1B. | |||
| ALP22535 | Q8BHK6-1(S23-G224) |
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| The CRACC/SLAMF7 protein is an autoligand receptor in the SLAM family that critically regulates immune cell activation and differentiation through homotypic or heterotypic interactions. It coordinates distinct immune responses, dependent on the presence or absence of the cytoplasmic linkers SH2D1A/SAP and/or SH2D1B/EAT-2. | |||