一种细胞黏附分子,属于免疫球蛋白超家族,在细胞间连接形成中起关键作用,并在多种肿瘤中高表达,成为癌症治疗的重要靶点。
| 产品号 | 产品名称 | 蛋白编码 | 图片 |
|---|---|---|---|
| ALP22717 |
Recombinant Biotinylated Nectin-4 IgV domain Protein,Human,HEK293,C-His-Avi 重组蛋白Biotinylated Nectin-4 IgV domain Protein,Human,HEK293,C-His-Avi |
Q96NY8-1(G32-L146) |
|
| The Nectin-4 Protein IgV domain is pivotal in cell adhesion, participating in trans-homophilic and -heterophilic interactions, notably with NECTIN1. While it doesn't serve as an alpha-herpesvirus entry receptor, it functions as a receptor for measles virus, enabling virus entry into host cells. This dual role underscores the importance of Nectin-4 in cell adhesion and its specific role as a measles virus infection receptor. | |||
| ALP22533 | Q8R007(G31-I349) |
|
|
| Nectin-4 Protein participates in cell adhesion, engaging in trans-homophilic interactions with other Nectin-4 molecules and trans-heterophilic interactions, notably with NECTIN1. It can self-associate, with its Ig-like V-type domain interacting with NECTIN1's Ig-like V-type domain and its C-terminus interacting with AFDN. | |||