表皮生长因子受体,一种跨膜酪氨酸激酶受体,与配体结合后激活下游信号通路,调控细胞增殖、分化和存活。
| 产品号 | 产品名称 | 蛋白编码 | 图片 |
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| ALP22329 | Q01279(L25-S647) |
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| The EGFR protein is a receptor tyrosine kinase that binds EGF family ligands and activates multiple signaling cascades. Ligand binding induces receptor homo- or heterodimerization, leading to autophosphorylation and recruitment of adapter proteins (such as GRB2). | |||
| ALP22330 | E7CXR8(L25-S646) |
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| EGFR Protein is a receptor tyrosine kinase that binds to ligands of the EGF family. EGFR Protein is involved in the regulation of NF-kappa-B , RAS-RAF-MEK-ERK , PI3 kinase-AKT , PLCgamma-PKC and STATs signaling pathways. EGFR Protein has calmodulin binding activity, epidermal growth factor binding activity and epidermal growth factor activating receptor activity. | |||
| ALP22332 | Q01279(L25-S647) |
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| The EGFR protein is a receptor tyrosine kinase that binds EGF family ligands and activates multiple signaling cascades. Ligand binding induces receptor homo- or heterodimerization, leading to autophosphorylation and recruitment of adapter proteins (such as GRB2). | |||
| ALP22333 | NP_001333870(L25-S378) |
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| The EGFR vIII protein is a transmembrane glycoprotein in the protein kinase superfamily that acts as a receptor for epidermal growth factor. It acts on the cell surface, binds to epidermal growth factor, triggers receptor dimerization and tyrosine autophosphorylation, and promotes cell proliferation. | |||
| ALP22241 | P00533-1(L25-S645) |
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| The EGFR protein is a receptor tyrosine kinase that can bind to a variety of ligands, such as EGF , TGFA, AREG, epigen , BTC, epiregulin , and HBEGF, to initiate signaling cascades that mediate cellular responses. This involves receptor dimerization, autophosphorylation and recruitment of adapter proteins such as GRB2, activating downstream pathways such as RAS-RAF-MEK-ERK, PI3-kinase-AKT, PLCgamma-PKC and STAT . | |||
| ALP22245 | P00533-1(L25-S645) |
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| EGFR is a transmembrane glycoprotein . EGFR binds to ligands, triggering receptor dimerization, inducing intracellular TK domain autophosphorylation, activating downstream Ras/MAPK, PI3K/Akt and other signaling pathways, and regulating cell proliferation, survival, migration and angiogenesis. | |||
| ALP22307 |
Recombinant Biotinylated EGFR Protein,Human,621a.a,HEK293,C-His |
P00533-1(L25-S645) |
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| The EGFR protein is a receptor tyrosine kinase that can bind to a variety of ligands, such as EGF , TGFA, AREG, epigen , BTC, epiregulin , and HBEGF, to initiate signaling cascades that mediate cellular responses. This involves receptor dimerization, autophosphorylation and recruitment of adapter proteins such as GRB2, activating downstream pathways such as RAS-RAF-MEK-ERK, PI3-kinase-AKT, PLCgamma-PKC and STAT . | |||
| ALP22488 | NP_001333870(L25-S378) |
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| The EGFRvIII protein is a transmembrane glycoprotein in the protein kinase superfamily that acts as a receptor for epidermal growth factor. It acts on the cell surface, binds to epidermal growth factor, triggers receptor dimerization and tyrosine autophosphorylation, and promotes cell proliferation. | |||