T细胞表面分化抗原，参与免疫识别与信号传导，如CD4和CD8分别辅助和杀伤功能，对免疫应答至关重要。
| 种属: |
|
|---|---|
| 表达系统: |
|
| 标签: |
|
| 产品号 | 产品名称 | 蛋白编码 | 图片 |
|---|---|---|---|
| ALP8091 |
Recombinant Cynomolgus B7-2/CD86 Protein,Cynomolgus,C-His,Expi293 |
G7NXR4(Tyr26-His240) |
|
| Cluster of differentiation 80 (also CD80 and B7-1) is a protein found on dendritic cells, activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28 and CTLA-4. | |||
| ALP8089 | P33681-1(Val35-Asn242) |
|
|
| Cluster of differentiation 80 (also CD80 and B7-1) is a protein found on dendritic cells, activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28 and CTLA-4. | |||
| ALP8092 | P42081-1(Leu26-Pro247) |
|
|
| B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the activation and regulation of T cell immunity. B7-1 and B7-2 do not form hetero-oligomers, underscoring the biological relevance of dimeric and monomeric state of B7-1 and B7-2, respectively. | |||
| ALP8179 |
Recombinant Cynomolgus CD161 Protein,Cynomolgus,C-His-Avi,Expi293 |
XP_005570142.1(Gln67-Leu227) |
|
| CD161 (NKRP1) is a lectin-like receptor present on NK cells and rare T-cell subsets. We have observed CD161 expression in some cases of T-cell prolymphocytic leukemia (T-PLL) and found it to be useful in follow-up and detection of disease after treatment. | |||
| ALP8228 |
Recombinant Human CD3E&CD3D/CD3 epsilon&CD3 delta Protein,Human,C-hFc,Expi293 重组蛋白Human CD3E&CD3D/CD3 epsilon&CD3 delta Protein,Human,C-hFc,Expi293 |
P07766(CD3E)(Asp23-Asp126)&P04234(CD3D)(Phe22-Ala105) |
|
| T-cell surface glycoprotein CD3 epsilon & CD3 delta chain, also known as CD3E & CD3D , are single-pass type I membrane proteins.When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. | |||
| ALP8217 |
Recombinant Cynomolgus CD3E&CD3D/CD3 epsilon&CD3 delta Protein,Cynomolgus,C-hFc,Expi293 重组蛋白Cynomolgus CD3E&CD3D/CD3 epsilon&CD3 delta Protein,Cynomolgus,C-hFc,Expi293 |
Q95LI5.2(CD3E)(Gln22-Asp117)&Q95LI8(CD3D)(Phe22-Ala105) |
|
| T-cell surface glycoprotein CD3 epsilon&CD3 delta chain, also known as CD3E & CD3D , are single-pass type I membrane proteins.When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. | |||
| ALP8229 |
Recombinant Human CD3E/CD3 epsilon monomer Protein,Human,C-hFc,Expi293 重组蛋白Human CD3E/CD3 epsilon monomer Protein,Human,C-hFc,Expi293 |
P07766(Asp23-Asp126(C119S,C222S)) |
|
| T-cell surface glycoprotein CD3 epsilon & CD3 gamma chain, also known as CD3E & CD3G , are single-pass type I membrane proteins.When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. | |||
| ALP8219 |
Recombinant Cynomolgus CD3E&CD3G/CD3 epsilon&CD3 gamma Protein,Cynomolgus,C-hFc,Expi293 重组蛋白Cynomolgus CD3E&CD3G/CD3 epsilon&CD3 gamma Protein,Cynomolgus,C-hFc,Expi293 |
Q95LI5.2(CD3E)(Gln22-Asp117)&Q95LI7(CD3G)(Gln23-Thr113) |
|
| T-cell surface glycoprotein CD3 epsilon & CD3 gamma chain, also known as CD3E & CD3G , are single-pass type I membrane proteins.When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. | |||
| ALP8220 |
Recombinant Cynomolgus CD3E/CD3 epsilon 1-27 peptide Protein,Cynomolgus,C-hFc-Avi,Expi293 重组蛋白Cynomolgus CD3E/CD3 epsilon 1-27 peptide Protein,Cynomolgus,C-hFc-Avi,Expi293 |
Q95LI5.2(Asp22-Thr48) |
|
| CD3E, is a single-pass type I membrane protein.CD3 (cluster of differentiation 3) T cell co-receptor helps to activate both the cytotoxic T cell (CD8 naive T cells) and also T helper cells (CD4 naive T cells). It consists of a protein complex and is composed of four distinct chains. In mammals, the complex contains a CD3γ chain, a CD3δ chain, and two CD3ε chains. | |||
| ALP8232 |
Recombinant Human CD3E&CD3G/CD3 epsilon&CD3 gamma Protein,Human,C-hFc,Expi293 重组蛋白Human CD3E&CD3G/CD3 epsilon&CD3 gamma Protein,Human,C-hFc,Expi293 |
P07766(CD3E)(Asp23-Asp126)&P09693(CD3G)(Gln23-Ser116) |
|
| T-cell surface glycoprotein CD3 epsilon & CD3 gamma chain, also known as CD3E & CD3G , are single-pass type I membrane proteins.When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. | |||
| ALP8222 |
Recombinant Human CD3E&CD3D/CD3 epsilon&CD3 delta Protein,Human,C-His,Expi293 重组蛋白Human CD3E&CD3D/CD3 epsilon&CD3 delta Protein,Human,C-His,Expi293 |
P07766(CD3E)(Asp23-Glu120)&P04234(CD3D)(Phe22-Ala105) |
|
| T-cell surface glycoprotein CD3 epsilon & CD3 delta chain, also known as CD3E & CD3D , are single-pass type I membrane proteins.When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. | |||
| ALP8233 |
Recombinant Human CD3E/CD3 epsilon 1-27 peptide Protein,Human,C-hFc-Avi,Expi293 重组蛋白Human CD3E/CD3 epsilon 1-27 peptide Protein,Human,C-hFc-Avi,Expi293 |
P07766(Asp23-Thr48) |
|
| CD3E, is a single-pass type I membrane protein.CD3 (cluster of differentiation 3) T cell co-receptor helps to activate both the cytotoxic T cell (CD8 naive T cells) and also T helper cells (CD4 naive T cells). It consists of a protein complex and is composed of four distinct chains. In mammals, the complex contains a CD3γ chain, a CD3δ chain, and two CD3ε chains. | |||
| ALP8227 |
Recombinant Human CD3E&CD3G/CD3 epsilon&CD3 gamma Protein,Human,C-His,Expi293 重组蛋白Human CD3E&CD3G/CD3 epsilon&CD3 gamma Protein,Human,C-His,Expi293 |
P07766(CD3E)(Asp23-Glu120)&P09693(CD3G)(Gln23-Gln106) |
|
| T-cell surface glycoprotein CD3 epsilon & CD3 gamma chain, also known as CD3E & CD3G , are single-pass type I membrane proteins.When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. | |||
| ALP8259 | P06127(Arg25-Asn371) |
|
|
| CD5: a type I transmembrane protein found on T cells, thymocytes, and some B cells that is a ligand for CD72 and is involved in cellular activation or adhesion; expressed in B-cell chronic lymphocytic leukemia and T-cell lymphoma. | |||
| ALP8261 |
Recombinant Rhesus macaque CD5 Protein,Rhesus macaque,C-His-Avi,Expi293 重组蛋白Rhesus macaque CD5 Protein,Rhesus macaque,C-His-Avi,Expi293 |
F6V5Q9(Arg25-Pro375) |
|
| CD5: a type I transmembrane protein found on T cells, thymocytes, and some B cells that is a ligand for CD72 and is involved in cellular activation or adhesion; expressed in B-cell chronic lymphocytic leukemia and T-cell lymphoma. | |||
| ALP8243 |
Recombinant Mouse CD3E&CD3D/CD3 epsilon&CD3 delta Protein,Mouse,C-hFc,Expi293 重组蛋白Mouse CD3E&CD3D/CD3 epsilon&CD3 delta Protein,Mouse,C-hFc,Expi293 |
P22646(CD3E)(Asp23-Asp108)&P04235(CD3D)(Phe22-Ala105) |
|
| T-cell surface glycoprotein CD3 epsilon & CD3 delta chain, also known as CD3E & CD3D , are single-pass type I membrane proteins.When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. | |||
| ALP8291 |
Recombinant Human CD8 alpha/CD8A Protein,Human,C-His-Avi,Expi293 |
P01732-1(Ser22-Asp182) |
|
| CD8 alpha enhances the responses of antigen-specific CTL activated through TCR through binding MHC class I, favoring lipid raft partitioning of TCR, and inducing intracellular signaling. CD8 alpha is also found on dendritic cells and rat macrophages, but whether CD8 alpha enhances responses of a partner receptor, like TCR, to activate these cells is not known. | |||
| ALP8283 | Q01151-1(Thr20-Ala143) |
|
|
| CD83 is a member of the immunoglobulin (Ig) superfamily and is expressed in membrane bound or soluble forms. Membrane CD83 (mCD83) can be detected on a variety of activated immune cells, although it is most highly and stably expressed by mature dendritic cells (DC). While CD83 is emerging as a promising immune modulator with therapeutic potential, some important aspects such as its ligand/s, intracellular signaling pathways and modulators of its expression are unclear. | |||
| ALP8292 |
Recombinant Mouse CD8 alpha/CD8A Protein,Mouse,C-His,Expi293 |
P01731-1(Lys28-Tyr196) |
|
| CD8 alpha enhances the responses of antigen-specific CTL activated through TCR through binding MHC class I, favoring lipid raft partitioning of TCR, and inducing intracellular signaling. CD8 alpha is also found on dendritic cells and rat macrophages, but whether CD8 alpha enhances responses of a partner receptor, like TCR, to activate these cells is not known. | |||
| ALP6639 |
Rhesus Macaque CD3D-CD3E Heterodimer Protein, Rhesus Macaque, HEK293, N-hFc 重组蛋白Rhesus Macaque CD3D-CD3E Heterodimer Protein, Rhesus Macaque, HEK293, N-hFc |
F6WI60 (F22-A105)& G7NCB9 (Q22-D117) |
|
| CD3D 蛋白是 T 淋巴细胞上 TCR-CD3 复合物的重要组成部分，对于适应性免疫反应至关重要。APC激活TCR后，CD3D与CD3E、CD3G和CD3Z一起通过ITAM传递信号并激活下游通路。 | |||
