单核细胞表面表达的一组分化抗原蛋白，参与免疫识别、黏附及信号转导，在炎症反应和抗原呈递中发挥关键作用。
| 产品号 | 产品名称 | 蛋白编码 | 图片 |
|---|---|---|---|
| ALP8594 |
Recombinant Human IL-1R2/IL-1 RII/CD121b Protein,Human,C-His,Expi293 重组蛋白Human IL-1R2/IL-1 RII/CD121b Protein,Human,C-His,Expi293 |
P27930/NP_004624.1(Phe14-Glu343) |
|
| Interleukin (IL)-1 has been reported to be involved in the development of tuberculosis (TB). IL1R1 and IL1R2 encode a cytokine receptor that belongs to the IL-1 receptor family.IL1R2 (Interleukin 1 Receptor Type 2) is a Protein Coding gene. Diseases associated with IL1R2 include Endometriosis and Mastitis. Among its related pathways are Hematopoietic cell lineage and IL-1 signaling pathway. Gene Ontology (GO) annotations related to this gene include interleukin-1 receptor activity and interleukin-1, type II, blocking receptor activity. | |||
| ALP8598 |
Recombinant Human IL-1R2/IL-1 RII/CD121b Protein,Human,C-hFc,Expi293 重组蛋白Human IL-1R2/IL-1 RII/CD121b Protein,Human,C-hFc,Expi293 |
P27930/NP_004624.1(Phe14-Glu343) |
|
| The IL-1 type II receptor (decoy RII) is a nonsignaling molecule the only established function of which is to capture IL-1 and prevent it from interacting with signaling receptor. The decoy RII is released in a regulated way from the cell surface. | |||
| ALP24805 | Q4FZY1(K20-S295) |
|
|
| CD68 is a protein belonging to the LAMP (lysosome-associated membrane protein) family. It is expressed primarily in macrophages, monocytes, and dendritic cells, serving as a marker for these immune cells. | |||
| ALP24809 | B1PLB1(E37-T291) |
|
|
| CD34 Protein is a transmembrane phosphoglycoprotein that exists on the surface of human and various animal cells. CD34 Protein is used as a cellular marker for hematopoietic stem cell sorting and as an islet endocrine cell marker. CD34 Protein plays an important role in cell adhesion, inflammatory cell chemotaxis, cell proliferation and differentiation, and enhancement of inflammatory response. | |||
| ALP24894 | R9PXZ7/NP_001258015.1(Q21-S243) |
|
|
| CD43 protein is an important leukocyte surface sialic acid protein that plays a key role in T cell regulation. It has a positive impact on T cell function, including activation, proliferation, differentiation, trafficking and migration, especially by helping T cells migrate to lymph nodes through ERM proteins. | |||
| ALP24975 | Q9DCG2-2(D21-H156) |
|
|
| CD302/CLEC13A Protein, a potential multifunctional C-type lectin receptor, may engage in endocytosis, phagocytosis, cell adhesion, and migration processes. | |||
| ALP24981 | AAI04994.1(G24-E443) |
|
|
| LILRB3/CD85a protein, as a receptor for class I MHC antigens, plays an indispensable role in immune recognition. Activation of LILRB3 occurs through binding to immune receptors such as FCGR2B and B cell receptors, resulting in downregulation of antigen-induced B cell activation. | |||
| ALP24983 | D3ZAD7/NP_001102548.1(T25-L242) |
|
|
| The CD150/SLAMF1 protein is an autoligand receptor in the SLAM family that complexly regulates the activation and differentiation of immune cells and is critical for innate and adaptive immune responses. CD150/SLAMF1 exhibits unique signaling in T lymphocytes and B cells through fine-tuning of cytoplasmic adapter proteins including SH2D1A/SAP and/or SH2D1B/EAT-2. | |||
| ALP24984 | Q78ZF5(E29-W440) |
|
|
| The CD131 protein is a cell surface receptor that plays a critical role in the immune response and controls the generation and differentiation of hematopoietic progenitor cells. | |||
| ALP24985 | XP_005587354(A19-H209) |
|
|
| Basigin, also called CD147 or EMMPRIN, is a transmembrane glycoprotein that belongs to the immunoglobulin superfamily with homology to both the immunoglobulin V domain and major histocompatibility complex class II antigen 尾-chain. Basigin is the receptor for cyclophilins, S100A9 and platelet glycoprotein VI . Basigin tightly associates with monocarboxylate transporters and is essential for their cell surface translocation and activities. | |||
| ALP25128 | F6QA53(K22-R220) |
|
|
| CD84/SLAMF5 protein is a self-ligand receptor in the SLAM family that regulates the activities of various immune cells through homotypic or heterotypic cell-cell interactions. It fine-tunes its function based on the presence or absence of small cytoplasmic adapter proteins, including SH2D1A/SAP and/or SH2D1B/EAT-2. | |||
| ALP25365 | AAC53219(S25-Y640) |
|
|
| LILRB3/CD85a protein, as a receptor for class I MHC antigens, plays an indispensable role in immune recognition. Activation of LILRB3 occurs through binding to immune receptors such as FCGR2B and B cell receptors, resulting in downregulation of antigen-induced B cell activation. | |||
| ALP25115 | Q5FVR3(D21-H165) |
|
|
| The CD302/CLEC13A protein emerged as a potential multifunctional C-type lectin receptor, indicating its widespread involvement in cellular processes. This protein has a potential role in endocytosis and phagocytosis and is involved in cellular clearance. | |||
| ALP25123 | AAC53219(S25-Y640) |
|
|
| LILRB3/CD85a protein, as a receptor for class I MHC antigens, plays an indispensable role in immune recognition.Activation of LILRB3 occurs through binding to immune receptors such as FCGR2B and B cell receptors, resulting in downregulation of antigen-induced B cell activation. | |||
| ALP22143 |
Recombinant Biotinylated CD64 Protein,Human,272a.a,HEK293,C-His-Avi |
P12314-1(Q16-T287) |
|
| CD64 protein, a high affinity receptor, mediates IgG effector functions, triggering antibody-dependent cellular cytotoxicity (ADCC). It interacts with IGHG1 and forms a signaling complex with FCERG1, contributing to immune responses. CD64 also interacts with FLNA, EPB41L2, LAT, PPL, HCK , and LYN to prevent degradation of FCGR1A and regulate immune function. | |||
| ALP22145 |
Recombinant Biotinylated Fc gamma RIIB/CD32b Protein,Human,HEK293,C-His-Avi 重组蛋白Biotinylated Fc gamma RIIB/CD32b Protein,Human,HEK293,C-His-Avi |
P31994-2/NP_001002274.1(A46-I224) |
|
| Fc gamma RIIB/CD32b protein is a low-affinity receptor for immunoglobulin gamma and plays a key role in immune responses. It mediates phagocytosis of immune complexes and regulates antibody production by B cells. | |||
| ALP22349 | AAH40261.1(A24-P247) |
|
|
| B7-2/CD86 protein negatively regulates T-cell activation by disrupting CD86 cluster formation, modulating the T-cell response, and influencing immune activation. | |||
| ALP22382 | Q96DU3-1(L28-K225) |
|
|
| SLAMF6 protein is an autoligand receptor in the SLAM family, which is critical for the activation and differentiation of immune cells and coordinates innate and adaptive immune responses. SLAMF6 is regulated by cytoplasmic adapters such as SH2D1A/SAP and/or SH2D1B/EAT-2, and can trigger the cytolytic activity of NK cells, including VAV1 phosphorylation and SH2D1B dependence. | |||
| ALP22427 | P27512-1(L20-R193) |
|
|
| CD40 protein is a TNFSF5/CD40LG receptor that transduces signals through the TRAF6 and MAP3K8 pathways, activates ERK in macrophages and B cells, and induces immunoglobulin secretion. CD40 exists in monomeric and homodimeric forms, interacts with TRAF proteins (TRAF1, TRAF2, TRAF3, TRAF5 and TRAF6) and crucially mediates cellular responses to external signals. | |||
| ALP22435 | P27930(F14-E343) |
|
|
| IL-1R2 is a competitive endogenous inhibitor of IL-1 signaling. IL-1R2 serves as a decoy receptor and competes with IL-1R1 for IL-1 , it can also form a complex with IL-1RAP once it binds IL-1 . IL-1R2 is implicated in various IL-1-mediated inflammatory diseases. | |||
