细胞表面分化抗原簇蛋白，用于鉴定和分类干细胞亚群，在干细胞研究和临床应用中作为关键标志物。
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| 产品号 | 产品名称 | 蛋白编码 | 图片 |
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| ALP8168 |
Recombinant Human CEACAM-5/CD66e Protein,Human,C-His-Avi,Expi293 |
P06731-1(Lys35-Ala685) |
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| Epithelial Cellular Adhesion Molecule (EpCAM), also known as KS1/4, gp40, GA733-2, 17-1A, and TROP‑1, is a 40 kDa transmembrane glycoprotein that consists of a 242 amino acid (aa) extracellular domain with two EGF‑like repeats, a 23 aa transmembrane segment, and a 26 aa cytoplasmic domain. | |||
| ALP8239 |
Recombinant Human CD36/SR-B3 Protein,Human,C-His-Avi,Expi293 |
P16671-1(Gly30-Asn439) |
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| CD36, alternatively known as platelet membrane glycoprotein IV (GPIV), GPIIIb, thrombospondin receptor, collagen receptor, fatty acid translocase (FAT), and scavenger receptor class B, member 3 (SR-B3), is an integral membrane glycoprotein that has multiple physiological functions.CD36 is a multifunctional glycoprotein that acts as receptor for a broad range of ligands. Ligands can be of proteinaceous nature like thrombospondin, fibronectin, collagen or amyloid-beta as well as of lipidic nature such as oxidized low-density lipoprotein (oxLDL), anionic phospholipids, long-chain fatty acids and bacterial diacylated lipopeptides. | |||
| ALP8242 | Q08857(Gly30-Lys439) |
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| CD36 (cluster of differentiation 36), also known as platelet glycoprotein 4, is a protein that in humans is encoded by the CD36 gene. The CD36 antigen is an integral membrane protein found on the surface of many cell types in vertebrate animals. It imports fatty acids inside cells and is a member of the class B scavenger receptor family of cell surface proteins. | |||
| ALP8043 | Q9BZW8-2 (C22-R221) |
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| Adamas-life ® 2B4 (CD244) is expressed by memory-phenotype CD8(+) T cells and all natural killer (NK) cells. The ligand for 2B4, CD48, is expressed on hematopoietic cells. 2B4 is conserved in humans and mice, and a number of reports have linked 2B4 with activation of lymphocytes.Engagement of 2B4 on NK cell surfaces with specific antibodies or CD48 can trigger cell mediated cytotoxicity, interferon γ secretion, phosphoinositol turnover and NK cell invasiveness. | |||
| ALP8044 | Q9BZW8-2 (C22-R221) |
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| Adamas-life ® 2B4 (CD244) is expressed by memory-phenotype CD8(+) T cells and all natural killer (NK) cells. The ligand for 2B4, CD48, is expressed on hematopoietic cells. 2B4 is conserved in humans and mice, and a number of reports have linked 2B4 with activation of lymphocytes.Engagement of 2B4 on NK cell surfaces with specific antibodies or CD48 can trigger cell mediated cytotoxicity, interferon γ secretion, phosphoinositol turnover and NK cell invasiveness. | |||
| ALP6578 | Q63116 (Q26-T522) |
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| CD117 也称酪氨酸蛋白激酶 KIT 或肥大/干细胞生长因子受体 (SCFR)，是一种细胞因子受体，表达于造血干细胞和其他细胞类型的表面。CD117 信号通路在细胞存活、增殖和分化过程中发挥重要作用。CD117 是一种原癌基因，与肿瘤的发生相关。 | |||
| ALP8329 |
Recombinant Human CEACAM-8/CD66b Protein,Human,C-His,Expi293 |
NP_001807.2(Gln35-Ser319) |
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| Eosinophils and their products are likely important in the pathophysiology of allergic diseases, such as bronchial asthma, and in host immunity to parasitic organisms. CD66b (CEACAM8, CGM6, NCA-95) is a single chain, GPI-anchored, highly glycosylated protein belonging to the carcinoembryonic Ag supergene family. CD66b is an activation marker for human granulocytes. | |||
| ALP8483 | P36888-1(Asn27-Asn541) |
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| The Flt-3 (fms-like tyrosine kinase) receptor, also named Flk-2 (fetal liver kinase) and Stk-1(stem cell tyrosine kinase) is a member of the class III subfamily of receptor tyrosine kinases that also includes KIT, the receptor for SCF and FMS, the receptor for M-CSF. Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1, and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases, including MAPK1/ERK2 and/or MAPK3/ERK1. | |||
| ALP8485 |
Recombinant Human FLT3/Flk-2 Protein,Human,C-His-Avi,Expi293 |
P36888-1(Asn27-Asn541) |
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| The Flt-3 (fms-like tyrosine kinase) receptor, also named Flk-2 (fetal liver kinase) and Stk-1(stem cell tyrosine kinase) is a member of the class III subfamily of receptor tyrosine kinases that also includes KIT, the receptor for SCF and FMS, the receptor for M-CSF. Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1, and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases, including MAPK1/ERK2 and/or MAPK3/ERK1. | |||
| ALP9351 |
Recombinant Cynomolgus E-Cadherin/Cadherin-1 Protein,Cynomolgus,C-His,Expi293 重组蛋白Cynomolgus E-Cadherin/Cadherin-1 Protein,Cynomolgus,C-His,Expi293 |
A0A2K5V299(Asp155-Pro708) |
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| E-cadherin is the core component of epithelial adherens junctions, essential for tissue development, differentiation, and maintenance. It is also fundamental for tissue barrier formation, a critical function of epithelial tissues. | |||
| ALP9441 |
Recombinant Cynomolgus FLT3/Flk-2 Protein,Cynomolgus,C-hFc,Expi293 |
A0A2K5VQ48(Gln28-Ser541) |
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| The Flt-3 (fms-like tyrosine kinase) receptor, also named Flk-2 (fetal liver kinase) and Stk-1(stem cell tyrosine kinase) is a member of the class III subfamily of receptor tyrosine kinases that also includes KIT, the receptor for SCF and FMS, the receptor for M-CSF. Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1, and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases, including MAPK1/ERK2 and/or MAPK3/ERK1. | |||
| ALP9442 | Q00342(Asn28-Ser544) |
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| Flt‑3 Ligand, also known as FL, is an alpha -helical cytokine that promotes the differentiation of multiple hematopoietic cell lineages.Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins. | |||
| ALP9828 | NP_001069(Phe25-Pro697) |
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| Tumor necrosis factor alpha (TNFα) is a pro-inflammatory cytokine that triggers the expression of inflammatory molecules, including other cytokines and cell adhesion molecules. TNFα induces the expression of intercellular cell adhesion molecule-1 and vascular cell adhesion molecule-1 (VCAM-1). VCAM-1 was originally identified as a cell adhesion molecule that helps regulate inflammation-associated vascular adhesion and the transendothelial migration of leukocytes, such as macrophages and T cells. | |||
| ALP9664 |
Recombinant Human c-MPL/Thrombopoietin R Protein,Human,C-His,Expi293 重组蛋白Human c-MPL/Thrombopoietin R Protein,Human,C-His,Expi293 |
P40238-1(Gln26-Trp491) |
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| The c-mpl gene encodes a member of the hematopoietic cytokine receptor superfamily. This gene was discovered through the study of a murine retrovirus which induces an acute myeloproliferative syndrome in mice.MPLV (for myeloproliferative leukemia virus) has transduced a truncated and constitutively activated form of the c-mpl receptor chain. High levels of c-mpl expression were detected in 45% of acute myeloid leukemia (AML). No correlation was found between c-mpl expression and the French-American-British classification subtype of AML. | |||
| ALP9671 | P43121(Val24-Gly559) |
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| METCAM/MUC18 is an integral membrane cell adhesion molecule (CAM) in the Ig-like gene super-family. It can carry out common functions of CAMs which is to perform intercellular interactions and interaction of cell with extracellular matrix in tumor microenvironment, to interact with various signaling pathways and to regulate general behaviors of cells.The above positive correlation is fortuitous; actually METCAM/MUC18 acts as a tumor and metastasis suppressor for the ovarian carcinoma cells. | |||
| ALP24805 | Q4FZY1(K20-S295) |
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| CD68 is a protein belonging to the LAMP (lysosome-associated membrane protein) family. It is expressed primarily in macrophages, monocytes, and dendritic cells, serving as a marker for these immune cells. | |||
| ALP24806 | Q07490(N27-C55) |
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| The CD24 protein plays a critical role in cellular differentiation in various cell types, possibly triggered by binding of lectin-like ligands to the CD24 carbohydrate.This signal is transduced through second messengers released from GPI anchors. | |||
| ALP24809 | B1PLB1(E37-T291) |
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| CD34 Protein is a transmembrane phosphoglycoprotein that exists on the surface of human and various animal cells. CD34 Protein is used as a cellular marker for hematopoietic stem cell sorting and as an islet endocrine cell marker. CD34 Protein plays an important role in cell adhesion, inflammatory cell chemotaxis, cell proliferation and differentiation, and enhancement of inflammatory response. | |||
| ALP25309 |
Recombinant Integrin alpha V Protein,Human,P. pastoris,N-His |
P06756(D891-T1048) |
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| Recombinant Integrin alpha V Protein, expressed in P. pastoris with N-terminal His tag. | |||
| ALP25313 | P11464-1/NP_001171754.1(Q35-P419) |
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| Pregnancy-specific beta-1-glycoprotein 1 (PSG1) is derived from the syncytiotrophoblast and reaches concentrations in the serum of term pregnant women of 100 to 290 mg/l. As an important component of the human placenta, PSG1's molecular signature within the immunoglobulin (Ig) superfamily contributes to its important role in supporting pregnancy. | |||
