血小板表面表达的CD分子，参与黏附、聚集和信号转导，在止血和血栓形成中发挥关键作用。
| 产品号 | 产品名称 | 蛋白编码 | 图片 |
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| ALP8294 | AAH01061(Arg206-Ala630) |
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| The type II transmembrane protein CD98, best known as the heavy chain of the heterodimeric amino acid transporters (HAT), is required for the surface expression and basolateral localization of this transporter complex in polarized epithelial cells. CD98 also interacts with beta1 integrins resulting in an increase in their affinity for ligand. In this study we explored the role of the transmembrane and cytoplasmic domains of CD98 on integrin-dependent cell adhesion and migration in polarized renal epithelial cells. | |||
| ALP24800 | Q12913-1(R997-A1337) |
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| DEP-1/CD148 protein is a tyrosine phosphatase that affects multiple targets such as CTNND1, FLT3 , PDGFRB, and EGFR , thereby affecting cellular processes such as adhesion, migration, proliferation, and differentiation. DEP-1/CD148 is critical in vascular development, regulating macrophage adhesion, platelet activation, and thrombosis, while negatively regulating cell proliferation and PDGF-stimulated migration. | |||
| ALP24804 | P28648(A103-V203) |
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| The CD63 protein serves as a cell surface receptor for TIMP1 and is critical for activating signaling cascades. It contributes to ITGB1 and integrin signaling, activating AKT , FAK/PTK2 and MAP kinases to promote cell survival, cytoskeletal reorganization, adhesion, spreading and migration. | |||
| ALP24809 | B1PLB1(E37-T291) |
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| CD34 Protein is a transmembrane phosphoglycoprotein that exists on the surface of human and various animal cells. CD34 Protein is used as a cellular marker for hematopoietic stem cell sorting and as an islet endocrine cell marker. CD34 Protein plays an important role in cell adhesion, inflammatory cell chemotaxis, cell proliferation and differentiation, and enhancement of inflammatory response. | |||
| ALP24845 | P14562(A22-N371) |
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| The LAMP1/CD107a protein is a lysosomal membrane glycoprotein that plays critical roles in lysosomal biogenesis, pH regulation, autophagy , and cholesterol homeostasis.It critically regulates lysosomal lumen pH by inhibiting the proton channel TMEM175, optimizing lysosomal acidification for efficient hydrolase activity. | |||
| ALP24890 | Q8VCN6(D29-G138) |
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| CD99 Protein facilitates T-cell adhesion and aids leukocytes in crossing the endothelial basement membrane during leukocyte extravasation. It functions alongside PECAM1 but acts independently. CD99 Protein forms a homodimer and interacts with PILRB. | |||
| ALP24891 | B4F7A5(D25-G127) |
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| CD99 protein is a member of the CD99 family and plays a key role in several important cellular processes such as immune response, cell adhesion and migration. It exerts a major influence on lymphocyte trafficking and is involved in the regulation of immune cell interactions. | |||
| ALP24893 | P15702(D20-G248) |
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| CD43 (mouse) is a major leukocyte surface sialic acid protein that plays a critical regulatory role in T cell function.It positively affects the activation, proliferation, differentiation, trafficking and migration of T cells, particularly by enhancing migration to lymph nodes through ERM proteins. | |||
| ALP24894 | R9PXZ7/NP_001258015.1(Q21-S243) |
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| CD43 protein is an important leukocyte surface sialic acid protein that plays a key role in T cell regulation. It has a positive impact on T cell function, including activation, proliferation, differentiation, trafficking and migration, especially by helping T cells migrate to lymph nodes through ERM proteins. | |||
| ALP25319 | XP_001094728.1(W42-A771) |
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| P-Selectin Protein, Rhesus Macaque (HEK293, His) is a member of the selectin family of cell adhesion molecules . P-selectin mediates leukocyte rolling on stimulated endothelial cells and heterotypic aggregation of activated platelets onto leukocytes. P-selectin mediates heterotypic aggregation of activated platelets to cancer cells and adhesion of cancer cells to stimulated endothelial cells. P-selectin glycoprotein ligand-1 (PSGL-1) is a major ligand for P-selectin. | |||
| ALP25356 | Q9R0T4(Q24-A713) |
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| Cadherin-1/CD324 protein, a calcium-dependent adhesion molecule, mediates cell processes. It interacts homophilically with other cadherin molecules, sorting and organizing cell types. CDH1 regulates adhesion, mobility, and proliferation of epithelial cells. It serves as an integrin ligand, suppressing invasion and promoting non-amyloidogenic degradation. CDH1 inhibits APP C99 and C83 production. | |||
| ALP22338 | P16109(W42-A771) |
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| P-selectin is a Ca (2+)-dependent receptor on myeloid cells that critically binds to sialic acid-Lewis X on neutrophils and monocytes, promoting the interaction between activated endothelial cells or platelets and leukocytes interaction. This binding primarily to SELPLG/PSGL1 and PODXL2 is critical for rapid rolling of leukocytes during early inflammation. | |||
| ALP22176 |
Recombinant Fc gamma RIIA/CD32a Protein,Human 183a.a,H167R,HEK293,C-His 重组蛋白Fc gamma RIIA/CD32a Protein,Human 183a.a,H167R,HEK293,C-His |
P12318-1(A36-I218, H167R) |
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| Fc gamma The RIIA/CD32a protein plays a key role as a low-affinity receptor that specifically binds to the Fc region of immunoglobulin gamma. It interacts with IgG to initiate cellular responses against pathogens, which is critical for immune regulation. | |||
| ALP22180 |
Recombinant Fc gamma RIIA/CD32a Protein,Rhesus Macaque,HEK293,C-His |
H9BMP0(Q34-I217) |
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| The Fc γ RIIA/CD32a protein plays a key role by specifically binding to the Fc region of immunoglobulin γ, acting as a low-affinity receptor. Fc γ RIIA/CD32a initiates cellular responses against pathogens and soluble antigens and plays an important role in immune regulation. Fc γ RIIA/CD32a interacts with PI3K and Syk . | |||
| ALP22181 | Q08722-1/NP_942088.1(Q19-P139) |
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| CD47 is an adhesion protein that regulates integrin signaling through G protein activation and serves as a receptor for thrombospondin THBS1, affecting signal transduction, cardiovascular homeostasis, inflammation, apoptosis , angiogenesis, self-renewal and Immunomodulatory. It regulates pulmonary endothelin EDN1 signaling, acts as a pressor in blood pressure regulation, and is critical for memory formation. | |||
| ALP22189 |
Recombinant Fc gamma RIIB/CD32b Protein,Cynomolgus,HEK293,C-His |
Q8SPW3/AAL92097.1(A45-P217) |
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| Fc γ RIIB/CD32b proteins exhibit low affinity as complexes or receptors that aggregate the immunoglobulin γFc region. ITIM phosphorylated by Fc γ RIIB/CD32b recruits inositol phosphatases SHIP1 and SHIP2, inhibits Ras activation, down-regulates MAPK activity, reduces PLC-γ function, and results in PKC activation. Inhibition of MAP kinase pathway and anti-apoptotic kinase Akt inhibit cell proliferation and survival. | |||
| ALP25249 |
Recombinant Integrin alpha V beta 3 Protein,Human,HEK293,C-His |
P06756-1(F31-V992) |
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| Integrin α V beta 3 proteins, specifically the α-V (ITGAV) subunit, are multifunctional receptors for ligands such as vitronectin and fibronectin and recognize RGD sequences. ITGAV: ITGB3 binds fractalkine and acts as a coreceptor in CX3CR1-dependent signaling. | |||
| ALP25309 |
Recombinant Integrin alpha V Protein,Human,P. pastoris,N-His |
P06756(D891-T1048) |
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| Recombinant Integrin alpha V Protein, expressed in P. pastoris with N-terminal His tag. | |||
| ALP25310 | P09803(D157-V709) |
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| Cadherin-1/CD324 is a calcium-dependent cell adhesion protein that orchestrates homogeneous interactions, promoting cell cohesion and potential cell type sorting. CDH1 regulates epithelial cell adhesion, mobility, and proliferation and acts as an invasive suppressor. | |||
| ALP25358 | Q9R0T4(Q24-A713) |
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| Cadherin-1/CD324 protein, a calcium-dependent adhesion molecule, mediates cell processes. It interacts homophilically with other cadherin molecules, sorting and organizing cell types. CDH1 regulates adhesion, mobility, and proliferation of epithelial cells. It serves as an integrin ligand, suppressing invasion and promoting non-amyloidogenic degradation. CDH1 inhibits APP C99 and C83 production. | |||
