血管内皮细胞表面表达的CD分子，参与细胞黏附、信号传导和免疫调节，在血管生成和炎症反应中发挥关键作用。
| 种属: |
|
|---|---|
| 表达系统: |
|
| 标签: |
|
| 产品号 | 产品名称 | 蛋白编码 | 图片 |
|---|---|---|---|
| ALP6832 | Q9ET61 (D24-K571) |
|
|
| CD93/C1qR1 蛋白是一种受体或较大复合物的组成部分，对于免疫识别和反应至关重要。它作为 C1q、甘露糖结合凝集素 (MBL2) 和肺表面活性蛋白 A (SPA) 的受体，表明在与多种免疫成分相互作用中发挥作用。 | |||
| ALP6609 | Q9CRA0 (G24-K263) |
|
|
| ART4/CD297 蛋白是一种含有单 ADP-核糖基化 (ART) 基序的蛋白质，参与肽基-精氨酸 ADP-核糖基化。它是 ADP-核糖基转移酶基因家族的成员。ART4在多种结构中表达，包括心血管系统、泌尿生殖系统、外皮系统、肝和感觉器官。此外，ART4在恶性疟原虫 (P. falciparum)的红细胞侵袭中发挥重要作用。 | |||
| ALP6706 | P24394 -1 (M26-Q231) |
|
|
| IL-4R alpha 是 IL-4 和 IL-13 受体共有的 α 亚基，最初发现于白细胞中。IL-4R alpha 耦连于 JAK1/2/3-STAT6 通路，参与促进 Th2 分化。IL-4R alpha/CD124, Human 由 825 个氨基酸 (M1-S825) 组成，存在跨膜结构域 (233-256 a.a) 和可溶性形式 (1-227 a.a)。可溶性 IL-4R (sIL-4R) 可抑制 IL-4 介导的细胞增殖和 T 细胞对 IL-5 的上调。IL-4R alpha/CD124, Human (M26-Q231) 在 HEK293 细胞中产生，带有 C- 末端 mFc 标记。 | |||
| ALP8093 | P42081 -1 (L26-P247) |
|
|
| B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the activation and regulation of T cell immunity. B7-1 and B7-2 do not form hetero-oligomers, underscoring the biological relevance of dimeric and monomeric state of B7-1 and B7-2, respectively. | |||
| ALP6784 | P18827 (Q18-E251) |
|
|
| Syndecan-1/CD138 蛋白是一种细胞表面蛋白聚糖，通过硫酸乙酰肝素和硫酸软骨素将细胞骨架与间质基质连接起来。它通过 SDCBP 和 PDCD6IP 调节外泌体生物合成。Syndecan-1/CD138 蛋白通过牙细胞中的 MSX1 途径诱导其自身表达，并与 CDCP1 和 TIAM1 相互作用。它还与 MDK 相互作用，参与多种细胞过程。 | |||
| ALP6825 | NP_001154885.1 (A139-A565) |
|
|
| CD98 是一种多功能蛋白质，预计可作为氨基酸跨膜转运蛋白并具有双链 RNA 结合活性。它参与羧酸转运和病毒进入，作用于 dsRNA 反应的上游，表明它具有多种功能。 | |||
| ALP24804 | P28648(A103-V203) |
|
|
| The CD63 protein serves as a cell surface receptor for TIMP1 and is critical for activating signaling cascades. It contributes to ITGB1 and integrin signaling, activating AKT , FAK/PTK2 and MAP kinases to promote cell survival, cytoskeletal reorganization, adhesion, spreading and migration. | |||
| ALP24809 | B1PLB1(E37-T291) |
|
|
| CD34 Protein is a transmembrane phosphoglycoprotein that exists on the surface of human and various animal cells. CD34 Protein is used as a cellular marker for hematopoietic stem cell sorting and as an islet endocrine cell marker. CD34 Protein plays an important role in cell adhesion, inflammatory cell chemotaxis, cell proliferation and differentiation, and enhancement of inflammatory response. | |||
| ALP24842 | O35370(I17-S517) |
|
|
| Thrombomodulin is an endothelial cell receptor that forms a 1:1 complex with thrombin and is essential for the conversion of protein C to activated protein Ca . Protein Ca then cleaves coagulation cofactors, reducing thrombin production. | |||
| ALP24845 | P14562(A22-N371) |
|
|
| The LAMP1/CD107a protein is a lysosomal membrane glycoprotein that plays critical roles in lysosomal biogenesis, pH regulation, autophagy , and cholesterol homeostasis.It critically regulates lysosomal lumen pH by inhibiting the proton channel TMEM175, optimizing lysosomal acidification for efficient hydrolase activity. | |||
| ALP24890 | Q8VCN6(D29-G138) |
|
|
| CD99 Protein facilitates T-cell adhesion and aids leukocytes in crossing the endothelial basement membrane during leukocyte extravasation. It functions alongside PECAM1 but acts independently. CD99 Protein forms a homodimer and interacts with PILRB. | |||
| ALP24891 | B4F7A5(D25-G127) |
|
|
| CD99 protein is a member of the CD99 family and plays a key role in several important cellular processes such as immune response, cell adhesion and migration. It exerts a major influence on lymphocyte trafficking and is involved in the regulation of immune cell interactions. | |||
| ALP24899 |
Recombinant MME/Neprilysin Protein,Rhesus Macaque,HEK293,N-His |
F7H3Y6(Y52-W750) |
|
| MME is a cell-surface peptidase member of the M13 family of zinc peptidases, which also includes endothelin converting enzymes (ECE-1 and ECE-2), KELL and PEX. MME is downregulated in nearly 50% of primary and metastatic prostate cancers. | |||
| ALP24986 | Q63072(R34-E293) |
|
|
| CD157 protein catalyzes the synthesis of cADPR from NAD(+) and hydrolyzes cADPR to ADPR. cADPR acts as a second messenger, releasing calcium from intracellular stores. CD157 protein may also contribute to pre-B cell growth. | |||
| ALP25317 | NP_075594.1(R22-E285) |
|
|
| FGFR-1 beta is a member of the FGFR family that interacts with fibroblast growth factors and regulates mitosis and differentiation. It specifically binds acidic and basic fibroblast growth factors and is involved in limb induction. | |||
| ALP25319 | XP_001094728.1(W42-A771) |
|
|
| P-Selectin Protein, Rhesus Macaque (HEK293, His) is a member of the selectin family of cell adhesion molecules . P-selectin mediates leukocyte rolling on stimulated endothelial cells and heterotypic aggregation of activated platelets onto leukocytes. P-selectin mediates heterotypic aggregation of activated platelets to cancer cells and adhesion of cancer cells to stimulated endothelial cells. P-selectin glycoprotein ligand-1 (PSGL-1) is a major ligand for P-selectin. | |||
| ALP25124 | XP_001105270(A23-K745) |
|
|
| TIE-2 Protein, a tyrosine-protein kinase, acts as a cell-surface receptor for ANGPT1, ANGPT2, and ANGPT4, exerting comprehensive control over angiogenesis, endothelial cell behavior, and vascular stability. It regulates diverse processes, including endothelial cell survival, proliferation, migration, adhesion, and actin cytoskeleton reorganization, while also playing a crucial role in maintaining vascular quiescence and preventing the leakage of pro-inflammatory plasma proteins and leukocytes from blood vessels. | |||
| ALP25187 | AAH14271.1(E26-Q176) |
|
|
| CD105/Endoglin Protein, Human (Trx-His) is an accessory receptor for transforming growth factor beta ( TGF-β ), and is expressed on endothelial cells. | |||
| ALP22338 | P16109(W42-A771) |
|
|
| P-selectin is a Ca (2+)-dependent receptor on myeloid cells that critically binds to sialic acid-Lewis X on neutrophils and monocytes, promoting the interaction between activated endothelial cells or platelets and leukocytes interaction. This binding primarily to SELPLG/PSGL1 and PODXL2 is critical for rapid rolling of leukocytes during early inflammation. | |||
| ALP22340 | AAH07533(F22-K644) |
|
|
| Neuropilin-1 protein plays an important role by binding to VEGF-165, possibly inhibiting its cellular binding and inducing apoptosis . This dual function suggests its role in regulating VEGF-mediated processes. | |||
