| 产品号 | 产品名称 | 蛋白编码 | 图片 |
|---|---|---|---|
| ALP8285 | Q96BF3-1(Leu23-Gly150) |
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| CD28H is constitutively expressed on all naive T cells. Repetitive antigenic exposure, however, induces a complete loss of CD28H on many T cells, and CD28H negative T cells have a phenotype of terminal differentiation and senescence. After extensive screening in a receptor array, a B7-like molecule, B7 homologue 5 (B7-H5), was identified as a specific ligand for CD28H. | |||
| ALP9032 | Q91V98(Gln18-Leu695) |
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| Colorectal cancer (CRC) is one of the most common cancers worldwide usually diagnosed in the advanced stage. The serum concentration of tumor endothelial marker 1 (TEM1) was measured and correlated with clinicopathological features to evaluate whether TEM1 might serve as a biomarker for early CRC diagnosis, progression, and prognosis. TEM1 can act as a potential diagnostic, progression, and prognostic serum biomarker for patients with CRC; TEM1 might be a good supplement for commonly used markers CEA and Ca 19-9. | |||
| ALP9036 |
Recombinant Cynomolgus Transferrin R/CD71 Protein,Cynomolgus,N-His,Expi293 重组蛋白Cynomolgus Transferrin R/CD71 Protein,Cynomolgus,N-His,Expi293 |
XP_005545315.1(Cys89-Phe760) |
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| The transferrin receptor (CD71) is known as a receptor for IgA1 on mesangial cells. The transcript and protein expression of glomerular CD71 was determined by real-time polymerase chain reaction and immunohistochemistry. Human mesangial cells (HMCs) were treated with sera from IgAN patients and expression levels of CD71 and inflammatory cytokine markers were compared according to disease status. | |||
| ALP9297 | Q62192(Thr21-Ser626) |
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| CD180, a related member of the Toll-like receptor family, is lost or underexpressed at the plasma membrane in circulating cells of various B-cell lymphomas except marginal zone lymphomas (MZL).CD180 can be considered as a single positive robust marker of MZL and should be therefore included in flow cytometry panels for the diagnosis of mature B-cell neoplasms. | |||
| ALP8974 | AAH10507.1(Thr20-Met345) |
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| CD14 is a lipopolysaccharide-binding protein, which functions as an endotoxin receptor. It is anchored to the cell surface by linkage to GPI. CD14 is strongly positive in monocytes and most tissue macrophages but is weakly expressed or negative in monoblasts and promonocytes. Myeloblasts and other granulocytic precursors do not express CD14, but neutrophils and a small proportion of B lymphocytes may weakly express CD14. T cells, dendritic cells, and platelets are CD14-negative. CD14 expression is reduced or lost in PNH because of the structural abnormality of GPI. | |||
| ALP9400 |
Recombinant Cynomolgus/Rhesus macaque DPPIV/CD26 Protein,Cynomolgus/Rhesus macaque,N-His,Expi293 重组蛋白Cynomolgus/Rhesus macaque DPPIV/CD26 Protein,Cynomolgus/Rhesus macaque,N-His,Expi293 |
XP_005573374(Cynomolgus)(Asn29-Pro766)/F6VRB0(Rhesus macaque)(Asn29-Pro766) |
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| CD26/dipeptidyl peptidase (DPP)IV is a membrane-bound protein found in many cell types of the body, and a soluble form is present in body fluids. There is longstanding evidence that various primary tumors and also metastases express DPPIV/CD26 to a variable extent. | |||
| ALP9337 | Q96BF3-1(Leu23-Gly150) |
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| CD28H is constitutively expressed on all naive T cells. Repetitive antigenic exposure, however, induces a complete loss of CD28H on many T cells, and CD28H negative T cells have a phenotype of terminal differentiation and senescence. After extensive screening in a receptor array, a B7-like molecule, B7 homologue 5 (B7-H5), was identified as a specific ligand for CD28H. | |||
| ALP9340 | Q9P2B2(Val26-Pro832) |
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| The membrane protein CD9P-1 is a major component of the tetraspanin web, a network of molecular interactions in the plasma membrane, in which it specifically associates with tetraspanins CD9 and CD81. All CD9P-1 isoforms associate with CD9 leading to additional level of complexity of this primary complex in the tetraspanin web. | |||
| ALP9342 | Q9NPY3(Thr22-Lys580) |
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| CD93 has been shown critical roles in inflammatory and immune diseases. CD93 silencing increased IL-6 and TSLP, but not IL-33 levels in culture supernatants. HDM-induced asthma mice showed significant airway hyperresponsiveness and inflammation with Th2 cytokine activation, along with decreased CD93 expression in bronchial epithelial cells and lung homogenates but increased serum CD93 levels. | |||
| ALP9344 | Q9WV91(Arg22-Pro832) |
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| The membrane protein CD9P-1 is a major component of the tetraspanin web, a network of molecular interactions in the plasma membrane, in which it specifically associates with tetraspanins CD9 and CD81. All CD9P-1 isoforms associate with CD9 leading to additional level of complexity of this primary complex in the tetraspanin web. | |||
| ALP9541 |
Recombinant Cynomolgus IL-18 R1/CD218a Protein,Cynomolgus,C-His,Expi293 重组蛋白Cynomolgus IL-18 R1/CD218a Protein,Cynomolgus,C-His,Expi293 |
A0A2K5V3J9(Cys22-Gly329) |
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| Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naïve T cells develop into IL-18 receptor (IL-18R) expressing Th1 cells, which increase IFN-γ production in response to IL-18 stimulation. | |||
| ALP9788 | Q9HCU0-1(Gln18-Leu687) |
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| Colorectal cancer (CRC) is one of the most common cancers worldwide usually diagnosed in the advanced stage. The serum concentration of tumor endothelial marker 1 (TEM1) was measured and correlated with clinicopathological features to evaluate whether TEM1 might serve as a biomarker for early CRC diagnosis, progression, and prognosis. TEM1 can act as a potential diagnostic, progression, and prognostic serum biomarker for patients with CRC; TEM1 might be a good supplement for commonly used markers CEA and Ca 19-9. | |||
| ALP24281 |
Recombinant Melanoma antigen preferentially/PRAME,Human,E. coli,N-His 重组蛋白Melanoma antigen preferentially/PRAME,Human,E. coli,N-His |
P78395(M1-N509) |
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| PRAME is located in the CRL2 E3 ubiquitin-protein ligase complex and directs ubiquitination and degradation, specifically targeting the truncated MSRB1/SEPX1 selenoprotein.It is recruited to active promoter regions and is involved in chromatin regulation. | |||
| ALP24333 | Q8R366(R26-T577) |
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| The CD316/IGSF8 protein plays a key role in functions related to CD81 and CD9, affecting oocyte fertilization and may affect HCV function. It regulates keratinocyte proliferation, acts as a negative regulator of cell motility, and binds to CD82 to inhibit prostate cancer cell migration. | |||
| ALP24380 | Q9UQV4/NP_055213.2(K28-T381) |
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| LAMP3/CD208 is a lysosomal glycoprotein that participates in the unfolded protein response (UPR) and contributes to protein degradation and cell survival, especially in the presence of proteasome dysfunction.It crucially promotes lysosome-autophagosome fusion and regulates autophagy . | |||
| ALP23899 | Q8BIF0-1(D26-A164) |
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| CD99L2 Protein is crucial in aiding leukocytes during a late stage of extravasation by facilitating the overcoming of the endothelial basement membrane barrier. Independently acting at the same site as PECAM1, CD99L2 serves as a homophilic adhesion molecule, even though its interactions may not be essential for cell aggregation. | |||
| ALP24235 | Q969P0-1(R28-T579) |
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| The CD316/IGSF8 protein plays a key role in multiple functions related to CD81 and CD9, affecting processes such as oocyte fertilization, hepatitis C virus function, and the regulation of keratinocyte proliferation and differentiation. | |||
| ALP25183 | Q8MJJ2(K28-T381) |
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| The LAMP3/CD208 protein is a lysosomal membrane glycoprotein that actively participates in the unfolded protein response (UPR), aiding protein degradation and cell survival during proteasome dysfunction. It is essential for lysosome-autophagosome fusion, where it regulates the autophagy process. | |||
| ALP25185 | H9ERH4(R22-K830) |
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| Prostaglandin F2 receptor inhibitor (PTGFRN) is a type I transmembrane Ig superfamily cell adhesion molecule . PTGFRN is involved in adipocyte maturation, muscle regeneration, tumor angiogenesis, metastasis, inhibition of follicle-stimulating hormone and luteinizing hormone secretion, and plasmodium infection. | |||
| ALP25113 |
Recombinant CD1D2-B2M Heterodimer Protein,Mouse,HEK293,C-His |
P11610(Q22-G305) |
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| The CD1D2 protein plays a crucial role as an antigen-presenting molecule, binding self and non-self glycolipids and presenting them to T-cell receptors on natural killer T-cells. In partnership with B2M, it mediates immune responses, and its interactions with MHC II and CD74 highlight its significance in the complex network of immune system regulation. | |||
