新生儿Fc受体，负责将母体IgG抗体转运至胎儿体内，并保护IgG免受降解，延长其半衰期。
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| 产品号 | 产品名称 | 蛋白编码 | 图片 |
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| ALP6756 |
Human FCRN-B2M Heterodimer Protein, Human, HEK293, C-6His 重组蛋白Human FCRN-B2M Heterodimer Protein, Human, HEK293, C-6His |
AAF72596 (A24-S297)& P61769 (I21-M119) |
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| FCGRT 是一种 IgG Fc 受体。Fc 受体表达受促炎细胞因子 TNF 上调，IFN-γ 下调。FCGRT 在调节 IgG 和血清白蛋白转换中发挥作用。FCGRT 的过表达还与肿瘤的不良预后有关。 | |||
| ALP8491 |
Recombinant Cynomolgus/Rhesus macaque FcRn Protein,Cynomolgus/Rhesus macaque,C-His,Expi293 重组蛋白Cynomolgus/Rhesus macaque FcRn Protein,Cynomolgus/Rhesus macaque,C-His,Expi293 |
Q8SPV9(FCGRT)(Ala24-Ser297)&Q8SPW0(B2M)(Ile21-Met119) |
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| The neonatal Fc receptor (FCRN) is an approximately 45 kDa transmembrane glycoprotein with structural homology to MHC class I proteins. It is widely expressed in endothelial and epithelial cells and plays an important role in IgG homeostasis and antigen presentation by dendritic cells.FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51, and p14 , and forms an MHC class I-like heterodimer. | |||
| ALP8492 | P55899-1(FCGRT)(Ala24-Ser297)&P61769-1(B2M)(Ile21-Met119) |
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| The neonatal Fc receptor (FCRN) is an approximately 45 kDa transmembrane glycoprotein with structural homology to MHC class I proteins. It is widely expressed in endothelial and epithelial cells and plays an important role in IgG homeostasis and antigen presentation by dendritic cells.FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51, and p14 , and forms an MHC class I-like heterodimer. | |||
| ALP8493 | Q61559(FCGRT)(Ser22-Ser297)&P01887(B2M)(Ile21-Met119) |
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| The neonatal Fc receptor (FCRN) is an approximately 45 kDa transmembrane glycoprotein with structural homology to MHC class I proteins. It is widely expressed in endothelial and epithelial cells and plays an important role in IgG homeostasis and antigen presentation by dendritic cells.FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51, and p14 , and forms an MHC class I-like heterodimer. | |||
| ALP6370 |
Recombinant Biotinylated Cynomolgus FCGRT & B2M Heterodimer Protein (C-His & AVI Tag) 重组蛋白Biotinylated Cynomolgus FCGRT & B2M Heterodimer Protein (C-His & AVI Tag) |
Q8SPV9(Ala24-Ser297)&Q8SPW0(Ile21-Met119) |
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| Recombinant Biotinylated Cynomolgus FCGRT & B2M Heterodimer Protein, expressed in HEK293 cells with C-terminal His tag and Avi tag. | |||
| ALP22197 | P55899(A24-S297) |
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| The FCGRT protein is a cell surface receptor that conveys passive humoral immunity through the selective uptake of monomeric IgG in milk. It binds IgG at the intestinal epithelium and forms an FcRn-IgG complex that is transcytosed across the epithelium, releasing IgG into the blood or tissue. | |||
| ALP22151 |
Recombinant FCGRT-B2M Heterodimer Protein,Cynomolgus,HEK293,C-His |
Q8SPV9(A24-S297) |
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| The FCGRT protein delivers passive immunity by binding to monomeric IgG and promoting its absorption from milk. It forms an FcRn-IgG complex, which is transcytosis by the intestinal epithelium and releases IgG into the bloodstream or interstitial fluid. | |||
| ALP22219 |
Recombinant Biotinylated FCRN-B2M Heterodimer Protein,Human,HEK293,C-His-Avi 重组蛋白Biotinylated FCRN-B2M Heterodimer Protein,Human,HEK293,C-His-Avi |
AAF72596(A24-S297) |
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| FCGRT is an IgG Fc receptor. Fc receptor expression is up-regulated by pro-inflammatory cytokines TNF and down-regulated by IFN-γ . FCGRT plays a role in regulating IgG and serum albumin conversion. Overexpression of FCGRT is also associated with poor prognosis of tumors. | |||
| ALP22165 |
Recombinant FCGRT-B2M Heterodimer Protein,Mouse,HEK293,C-His |
Q61559(S22-V301) |
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| The FCRN protein is a cell surface receptor that conveys passive humoral immunity through the selective uptake of monomeric IgG in milk. | |||
| ALP22168 |
Recombinant Biotinylated FCGRT-B2M Heterodimer Protein,Mouse,HEK293,C-His 重组蛋白Biotinylated FCGRT-B2M Heterodimer Protein,Mouse,HEK293,C-His |
Q61559(S22-S297) |
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| The FCRN protein is a cell surface receptor that conveys passive humoral immunity through the selective uptake of monomeric IgG in milk. | |||
| ALP22233 | P13599(A23-S298) |
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| The FCGRT-B2M heterodimeric protein is a cell surface receptor that interacts with IgG and albumin and contributes to effective humoral immunity. | |||
| ALP22141 | P55899(A24-S297) |
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| The FCGRT protein is a cell surface receptor that conveys passive humoral immunity through the selective uptake of monomeric IgG in milk. It binds IgG at the intestinal epithelium and forms an FcRn-IgG complex that is transcytosed across the epithelium, releasing IgG into the blood or tissue. | |||
| ALP22199 | P13599(A23-S298) |
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| The FCGRT-B2M heterodimeric protein is a cell surface receptor that interacts with IgG and albumin and contributes to effective humoral immunity. | |||
