免疫球蛋白E的Fc段受体，主要存在于肥大细胞和嗜碱性粒细胞表面，介导过敏反应和抗寄生虫免疫。
| 产品号 | 产品名称 | 蛋白编码 | 图片 |
|---|---|---|---|
| ALP8223 |
Recombinant Human CD23/Fc epsilon RII Protein,Human,N-His,Expi293 |
P06734-1(Asp48-Ser321) |
|
| CD23 is the low-affinity receptor for immunoglobulin (Ig)E and plays important roles in the regulation of IgE responses. CD23 can be cleaved from cell surfaces to yield a range of soluble CD23 (sCD23) proteins that have pleiotropic cytokine-like activities. | |||
| ALP8443 |
Recombinant Mouse Fc Epsilon RI alpha/FCER1a Protein,Mouse,C-hFc,Expi293 重组蛋白Mouse Fc Epsilon RI alpha/FCER1a Protein,Mouse,C-hFc,Expi293 |
P20489(Ala24-Gln204) |
|
| Known susceptibility genes to atopy and asthma have been identified by linkage or associations with clinical phenotypes, including total serum IgE levels. IgE-mediated sensitivity reactions require a high-affinity IgE receptor (FcepsilonRI), which immobilizes the immunoglobulin on the surface of the effector cells, mostly mast cells and basophils. Similarly to the previously investigated beta subunit of the receptor, FCER1A is a good candidate for a quantitative trait locus (QTL) in allergic diseases, and appears to participate in the systemic regulation of IgE levels. | |||
| ALP8442 |
Recombinant Human Fc epsilon RI alpha/FCER1a Protein,Human,C-His,Expi293 重组蛋白Human Fc epsilon RI alpha/FCER1a Protein,Human,C-His,Expi293 |
P12319-1(Val26-Gln205) |
|
| Known susceptibility genes to atopy and asthma have been identified by linkage or associations with clinical phenotypes, including total serum IgE levels. IgE-mediated sensitivity reactions require a high-affinity IgE receptor (FcepsilonRI), which immobilizes the immunoglobulin on the surface of the effector cells, mostly mast cells and basophils. Similarly to the previously investigated beta subunit of the receptor, FCER1A is a good candidate for a quantitative trait locus (QTL) in allergic diseases, and appears to participate in the systemic regulation of IgE levels. | |||
| ALP9433 |
Recombinant Human Fc epsilon RI alpha/FCER1a Protein,Human,C-hFc,Expi293 重组蛋白Human Fc epsilon RI alpha/FCER1a Protein,Human,C-hFc,Expi293 |
P12319-1(Val26-Gln205) |
|
| Known susceptibility genes to atopy and asthma have been identified by linkage or associations with clinical phenotypes, including total serum IgE levels. IgE-mediated sensitivity reactions require a high-affinity IgE receptor (FcepsilonRI), which immobilizes the immunoglobulin on the surface of the effector cells, mostly mast cells and basophils. Similarly to the previously investigated beta subunit of the receptor, FCER1A is a good candidate for a quantitative trait locus (QTL) in allergic diseases, and appears to participate in the systemic regulation of IgE levels. | |||
| ALP22228 | P20693-1(E50-P331) |
|
|
| CD23/Fc epsilon RII Protein, a low-affinity receptor for IgE and CR2/CD21, regulates IgE production and B cell differentiation. On B cells, it initiates IgE-dependent antigen uptake and presentation to T cells. On macrophages, IgE binding induces intracellular killing of parasites through the L-Arginine-nitric oxide pathway. CD23/Fc epsilon RII homotrimer interacts with IGHE to regulate IgE homeostasis and with CR2/CD21 for binding. | |||
| ALP22227 | Q6AZ45(E50-P331) |
|
|
| CD23, also known as Fc epsilon Receptor II (Fc epsilon RII), is a low-affinity receptor for immunoglobulin E ( IgE ) and complement receptor 2 (CR2/CD21). CD23 regulates IgE production and B-cell differentiation, aiding in IGE-dependent antigen uptake. | |||
| ALP22202 |
Recombinant Fc epsilon RIA/FCER1A Protein,Human,E. coli,N-His-SUMO |
P12319(V26-Q205) |
|
| The Fc epsilon RIA/FCER1A protein is a high-affinity receptor for IgE and critically mediates IgE effector function in myeloid cells. After binding to IgE and cross-linking with antigen, it activates signaling pathways that induce myeloid cell activation and differentiation. | |||
