免疫球蛋白Fc区是抗体分子的恒定区，负责与细胞表面受体结合，介导抗体效应功能，如抗体依赖性细胞毒作用和补体激活。
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| 产品号 | 产品名称 | 蛋白编码 | 图片 |
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| ALP6632 | P01857 -1 (E99-K330, C103S) |
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| IgG1蛋白是免疫球蛋白重链的恒定区，在体液免疫识别阶段充当受体。它触发 B 淋巴细胞克隆扩增并分化为分泌免疫球蛋白的浆细胞。 | |||
| ALP6808 | P01861 -1 (E99-G326) |
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| IgG4 Fc 是免疫球蛋白重链的恒定区，它构成了体液免疫中至关重要的抗体的骨架。B 淋巴细胞产生糖蛋白抗体，在抗原结合后启动克隆扩增。 | |||
| ALP6661 |
Human IgG1 Protein (D239E, L241M), Human, HEK293, No Tag 重组蛋白Human IgG1 Protein (D239E, L241M), Human, HEK293, No Tag |
P01857 -1 (D104-K330, D239E, L241M) |
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| IgG1蛋白是免疫球蛋白重链的恒定区，在体液免疫识别阶段充当受体。它触发 B 淋巴细胞克隆扩增并分化为分泌免疫球蛋白的浆细胞。 | |||
| ALP22172 | P01860-1(E99-K377) |
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| The IgG3 Fc protein is the constant region of an immunoglobulin heavy chain that acts as a receptor for a specific antigen. | |||
| ALP22175 | P03987-2(E97-T306) |
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| IgG3 Fc Protein is the high conserved Fc segment of IgG3 (Immunoglobulin G3). Mouse IgG3 Fc protein is involved in several processes, such as activation of immune response, B-cell signaling, complement activation. | |||
| ALP9515 | F6TQW2(Ile97-Ser330) |
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| Mouse IgG2c is a subclass of mouse antibody IgG, it can bind FcγRIV with high affinity and the Fc loop residues of mouse IgG2c promote greater receptor-binding affinity than mouse IgG2b or human IgG1. | |||
| ALP8585 | P01857(Asp103-Lys330) |
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| IgG1 is most abundant in serum among the four IgG subclasses (IgG1, 2, 3 and 4) and binds to Fc receptors (FcγR) on phagocytic cells with high affinity. Fc fragment is demonstrated to mediate phagocytosis, trigger inflammation, and target Ig to particular tissues.IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases. | |||
| ALP8586 | P01861(Glu99-Gly326) |
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| It is known as a IgG4-related disease and its differentiation is based on the analysis of IgG4 levels in the affected tissues. The IgG4-related disease is considered to be a generalized pathological process involving a wide spectrum of various disorders that may affect distant organs. | |||
| ALP8780 | P01868(Val98-Lys324) |
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| Recombinant murine Fc fragment contains the hinge region, CH2, and CH3 region of the mouse IgG1 isotype. IgG1 is most abundant in serum among the four IgG subclasses (IgG1, 2, 3 and 4) and binds to Fc receptors (FcγR) on phagocytic cells with high affinity. Fc fragment is demonstrated to mediate phagocytosis, trigger inflammation, and target Ig to particular tissues. | |||
| ALP8579 |
Recombinant Cynomolgus IgE Protein,Cynomolgus,C-His-Avi,Expi293 |
G8F4W7(Cys208-Lys429) |
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| Immunoglobulin E (IgE) is well known for its role in allergic disease, the manifestations of which are mediated through its two Fc receptors, FcεRI and CD23 (FcεRII). IgE and its interactions with these receptors are therefore potential targets for therapeutic intervention, and exciting progress has been made in this direction. Furthermore, recent structural studies of IgE-Fc, the two receptors, and of their complexes, have revealed a remarkable degree of plasticity at the IgE-CD23 interface and an even more remarkable degree of dynamic flexibility within the IgE molecule. | |||
| ALP8580 | P06336(Val91-Ser421) |
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| Immunoglobulin E (IgE) is well known for its role in allergic disease, the manifestations of which are mediated through its two Fc receptors, FcεRI and CD23 (FcεRII). IgE and its interactions with these receptors are therefore potential targets for therapeutic intervention, and exciting progress has been made in this direction. Furthermore, recent structural studies of IgE-Fc, the two receptors, and of their complexes, have revealed a remarkable degree of plasticity at the IgE-CD23 interface and an even more remarkable degree of dynamic flexibility within the IgE molecule. | |||
| ALP8581 | P06336(Asp198-Ser421) |
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| Immunoglobulin E (IgE) is well known for its role in allergic disease, the manifestations of which are mediated through its two Fc receptors, FcεRI and CD23 (FcεRII). IgE and its interactions with these receptors are therefore potential targets for therapeutic intervention, and exciting progress has been made in this direction. Furthermore, recent structural studies of IgE-Fc, the two receptors, and of their complexes, have revealed a remarkable degree of plasticity at the IgE-CD23 interface and an even more remarkable degree of dynamic flexibility within the IgE molecule. | |||
| ALP6297 | P01854-1(Cys105-Lys428,E203K) |
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| Recombinant Human IgE-Fc Protein, expressed in HEK293 cells with C-terminal His tag. | |||
| ALP22203 | P01867-2(E97-K335) |
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| IgG2B Fc Protein is a member of many immunoglobulin G developed and secreted by effective B cells. | |||
| ALP22220 | P0DOY2(G1-S106) |
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| The Ig Lambda Constant 2 protein is part of the constant region of the immunoglobulin light chain. It acts as a receptor during the recognition phase of humoral immunity, triggering B lymphocyte expansion and differentiation into plasma cells. | |||
| ALP22221 | P01834(T2-C107) |
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| Ig kappa protein is the constant region of an immunoglobulin light chain and is part of a membrane-bound or secreted glycoprotein produced by B lymphocytes. | |||
| ALP22223 | P01591/NP_653247.1(Q23-D159) |
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| The IgJ protein links IgM or IgA monomers, nucleating IgM pentamers and inducing IgA dimer or polymer formation. It also binds these immunoglobulins to the secretory component. As part of the sIgA complex, IgJ integrates with IgA monomers, the J chain, and the secretory component (PIGR proteolytic product). | |||
| ALP22225 | P20760(V98-K322) |
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| Ig gamma-2A chain C region ( IgG2a ) is one of the IgG antibodies subclasses and responses to an antigen. IgG2a plays a crucial role in the adaptive immune response. | |||
| ALP22234 | P01857-1(E99-K330) |
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| Recombinant Biotinylated IgG1 Protein, expressed in HEK293 cells with C-terminal Avi tag. | |||
| ALP22230 | AAX73259.1(E1-S243) |
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| IgG2B Fc Protein, Llama (HEK293) is the recombinant IgG2B Fc protein, expressed by HEK293 , with tag free. | |||
