| 货号 | 产品名称 | 蛋白编码 | 图片 |
|---|---|---|---|
| ALP8046 |
Biotinylated Human TPBG/5T4 Protein,Human,C-His-Avi,Expi293 重组蛋白Biotinylated Human TPBG/5T4 Protein,Human,C-His-Avi,Expi293 |
Q13641 (S32-S355) |
|
| The oncofetal tumor-associated antigen 5T4 (TBGP) has been linked with CSC properties in several different malignancies. 5T4 has functional attributes that are relevant to the spread of tumors including through EMT, CXCR4/CXCL12, Wnt, and Hippo pathways which may all contribute through the mobilization of CSCs. | |||
| ALP8056 |
Biotinylated Human ALCAM/CD166 Protein (Primary Amine Labeling) ,Human,C-His,Expi293 重组蛋白Biotinylated Human ALCAM/CD166 Protein (Primary Amine Labeling) ,Human,C-His,Expi293 |
Q13740 (W28-A526) |
|
| Brain metastasis (BM) in non-small-cell lung cancer (NSCLC) has a very poor prognosis. Recent studies have demonstrated the importance of cell adhesion molecules in tumor metastasis. Elevated levels of ALCAM expression promote BM formation in NSCLC through increased tumor cell dissemination and interaction with the brain endothelial cells. Therefore, ALCAM could be targeted to reduce the occurrence of BM. | |||
| ALP8082 | P30530 -1 (A26-P449) |
|
|
| Adamas-life ® Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell proliferation, chemotherapy resistance, invasion, and metastasis in several human cancers, such as lung, breast, and pancreatic cancers. | |||
| ALP8103 |
Biotinylated Human BAFFR/TNFRSF13C Protein,Human,C-His-Avi,Expi293 重组蛋白Biotinylated Human BAFFR/TNFRSF13C Protein,Human,C-His-Avi,Expi293 |
Q96RJ3 -1 (S7-A71) |
|
| Adamas-life ® BAFF binds to three TNF receptor superfamily members: B-cell maturation antigen (BCMA/TNFRSF17), transmembrane activator and calcium-modulator and cyclophilin ligand interactor (TACI/TNFRSF13B) and BAFF receptor (BAFF R/BR3/TNFRSF13C). These receptors are type III transmembrane proteins that lack a signal peptide. Whereas TACI and BCMA bind BAFF and another TNF superfamily ligand, APRIL (a proliferation-inducing ligand), BAFF R selectively binds BAFF. | |||
| ALP8109 |
Biotinylated Human 4-1BB/TNFRSF9 Protein,Human,C-His-Avi,Expi293 重组蛋白Biotinylated Human 4-1BB/TNFRSF9 Protein,Human,C-His-Avi,Expi293 |
Q07011 (L24-Q186) |
|
| 4-1BB, is also known as CD137, is a type 2 transmembrane glycoprotein receptor belonging to the TNF superfamily.CD137 can be expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, CD137 expression is found on dendritic cells, B cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation. | |||
| ALP8111 |
Biotinylated Human 4-1BB/TNFRSF9 Protein,Human,C-hFc-Avi,Expi293 重组蛋白Biotinylated Human 4-1BB/TNFRSF9 Protein,Human,C-hFc-Avi,Expi293 |
Q07011 (L24-Q186) |
|
| 4-1BB, is also known as CD137, is a type 2 transmembrane glycoprotein receptor belonging to the TNF superfamily.CD137 can be expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, CD137 expression is found on dendritic cells, B cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation. | |||
| ALP8143 |
Biotinylated Human B7-H3 (4Ig) /B7-H3b Protein,Human,C-His-Avi,Expi293 重组蛋白Biotinylated Human B7-H3 (4Ig) /B7-H3b Protein,Human,C-His-Avi,Expi293 |
Q5ZPR3 -1 (G27-T461) |
|
| Adamas-life ® B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig ‑ B7 ‑ H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. | |||
| ALP8145 |
Biotinylated Human B7-H2/ICOSLG Protein,Human,C-His-Avi,Expi293 重组蛋白Biotinylated Human B7-H2/ICOSLG Protein,Human,C-His-Avi,Expi293 |
O75144 -1 (D19-S258) |
|
| Adamas-life ® B7-H2, also known as B7-related protein (B7RP1), ICOS Ligand, and CD275, is an approximately 60 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. B7-H2 is a ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. | |||
| ALP8146 |
Biotinylated Human B7-H6 Protein,Human,C-His-Avi,Expi293 重组蛋白Biotinylated Human B7-H6 Protein,Human,C-His-Avi,Expi293 |
Q68D85 (D25-S262) |
|
| Adamas-life ® B7-H6 is a glycosylated member of the B7 family of immune co ‑ stimulatory proteins. which is a ligand for the NK cell activating receptor NKp30, was targeted to create a CAR that targets multiple tumor types. B7H6 is expressed on various primary human tumors, including leukemia, lymphoma and gastrointestinal stromal tumors, but it is not constitutively expressed on normal tissues. | |||
| ALP8066 |
Biotinylated Human ANGPTL2/Angiopoietin-like 2 Protein,Human,C-His-Avi,Expi293 重组蛋白Biotinylated Human ANGPTL2/Angiopoietin-like 2 Protein,Human,C-His-Avi,Expi293 |
Q9UKU9 -1 (T260-H493) |
|
| Angiopoietin-like 2 (ANGPTL2) is a proinflammatory protein belonging to the angiopoietin-like family. ANGPTL2 is secreted and detected in the systemic circulation. Different observational clinical studies reported that circulating levels of ANGPTL2 increase significantly in various chronic inflammatory diseases and showed associations between ANGPTL2 levels and diagnosis and/or prognosis of cardiovascular diseases, diabetes, chronic kidney disease, and various types of cancers. | |||
| ALP8094 |
Biotinylated Human B7-2/CD86 Protein,Human,C-His-Avi,Expi293 重组蛋白Biotinylated Human B7-2/CD86 Protein,Human,C-His-Avi,Expi293 |
P42081 -1 (L26-P247) |
|
| Adamas-life ® B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the activation and regulation of T cell immunity. B7-1 and B7-2 do not form hetero-oligomers, underscoring the biological relevance of dimeric and monomeric state of B7-1 and B7-2, respectively. | |||
| ALP8119 |
Biotinylated Human BCMA/TNFRSF17 Protein,Human,C-His-Avi,Expi293 重组蛋白Biotinylated Human BCMA/TNFRSF17 Protein,Human,C-His-Avi,Expi293 |
Q02223 (M1-A54) |
|
| Adamas-life ® B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene.TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF). | |||
| ALP8122 |
Biotinylated Human BCMA/TNFRSF17 Trimer Protein,Human,C-His-Avi,Expi293 重组蛋白Biotinylated Human BCMA/TNFRSF17 Trimer Protein,Human,C-His-Avi,Expi293 |
Q02223 (M1-A54) |
|
| Adamas-life ® B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene.TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF). | |||
| ALP8125 |
Biotinylated Mouse BCMA/TNFRSF17 Protein,Mouse,C-His-Avi,Expi293 重组蛋白Biotinylated Mouse BCMA/TNFRSF17 Protein,Mouse,C-His-Avi,Expi293 |
O88472 -1 (M1-T49) |
|
| B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene.TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF). | |||
| ALP8149 |
Cynomolgus Serum Albumin Protein,Cynomolgus,C-His,Expi293 重组蛋白Cynomolgus Serum Albumin Protein,Cynomolgus,C-His,Expi293 |
A2V9Z4 (D25-A608) |
|
| Albumins are multifunctional proteins present in the blood serum of animals. They can bind and transport a wide variety of ligands which they accommodate due to their conformational flexibility. Serum albumins are highly conserved both in amino acid sequence and three-dimensional structure. Several mammalian and avian serum albumins (SAs) are also allergens. Sensitization to one of the SAs coupled with the high degree of conservation between SAs may result in cross-reactive antibodies in allergic individuals. | |||
| ALP8150 | P02768 -1 (D25-L609) |
|
|
| Human serum albumin (HSA), the most prominent protein in plasma, binds different classes of ligands at multiple sites. HSA provides a depot for many compounds, affects pharmacokinetics of many drugs, holds some ligands in a strained orientation providing their metabolic modification, renders potential toxins harmLess transporting them to disposal sites, accounts for most of the antioxidant capacity of human serum, and acts as a NO-carrier. | |||
| ALP8151 |
Biotinylated Human Serum Albumin Protein,Human,C-His-Avi,Expi293 重组蛋白Biotinylated Human Serum Albumin Protein,Human,C-His-Avi,Expi293 |
P02768 -1 (D25-L609) |
|
| Adamas-life ® Human serum albumin (HSA), the most prominent protein in plasma, binds different classes of ligands at multiple sites. HSA provides a depot for many compounds, affects pharmacokinetics of many drugs, holds some ligands in a strained orientation providing their metabolic modification, renders potential toxins harmless transporting them to disposal sites, accounts for most of the antioxidant capacity of human serum, and acts as a NO-carrier. | |||
| ALP8154 | Q7Z6A9 -1 (K31-S150) |
|
|
| Adamas-life ® B- and T-lymphocyte attenuator (BTLA; CD272) is a 35 kDa type I transmembrane glycoprotein in the CD28 family of T cell costimulatory molecules. BTLA is a inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2. BTLA may interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14. | |||
| ALP8058 |
Biotinylated Human ALCAM/CD166 Protein,Human,C-His-Avi,Expi293 重组蛋白Biotinylated Human ALCAM/CD166 Protein,Human,C-His-Avi,Expi293 |
Q13740 (W28-A526) |
|
| Brain metastasis (BM) in non-small-cell lung cancer (NSCLC) has a very poor prognosis. Recent studies have demonstrated the importance of cell adhesion molecules in tumor metastasis. Elevated levels of ALCAM expression promote BM formation in NSCLC through increased tumor cell dissemination and interaction with the brain endothelial cells. Therefore, ALCAM could be targeted to reduce the occurrence of BM. | |||
| ALP8161 |
Biotinylated Human BTN1A1/Butyrophilin Protein,Human,C-His-Avi,Expi293 重组蛋白Biotinylated Human BTN1A1/Butyrophilin Protein,Human,C-His-Avi,Expi293 |
Q13410 (A27-R242) |
|
| Butyrophilin 1A1 (BTN1A1) is one of the membrane proteins that surrounds LD, BTN1A1 plays an important role in regulating LD synthesis via a mechanism involving membrane phospholipid composition. | |||
