生物素标记蛋白利用生物素与链霉亲和素之间极高的亲和力（Kd约10⁻¹⁵ M）进行检测和纯化。生物素通过NHS酯、马来酰亚胺或BirA连接酶定点标记偶联蛋白质，标记后可用于ELISA、Western blot信号放大和链霉亲和素磁珠亲和纯化。定点生物素化相比随机标记能更好保留蛋白活性。
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| 产品号 | 产品名称 | 蛋白编码 | 图片 |
|---|---|---|---|
| ALP8046 |
Biotinylated Human TPBG/5T4 Protein,Human,C-His-Avi,Expi293 重组蛋白Biotinylated Human TPBG/5T4 Protein,Human,C-His-Avi,Expi293 |
Q13641 (S32-S355) |
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| The oncofetal tumor-associated antigen 5T4 (TBGP) has been linked with CSC properties in several different malignancies. 5T4 has functional attributes that are relevant to the spread of tumors including through EMT, CXCR4/CXCL12, Wnt, and Hippo pathways which may all contribute through the mobilization of CSCs. | |||
| ALP8052 |
Biotinylated Human ACE2/ACEH Protein,Human,C-hFc-Avi,Expi293 重组蛋白Biotinylated Human ACE2/ACEH Protein,Human,C-hFc-Avi,Expi293 |
Q9BYF1 -1 (Q18-S740) |
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| Adamas-life ® ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. | |||
| ALP8058 |
Biotinylated Human ALCAM/CD166 Protein,Human,C-His-Avi,Expi293 重组蛋白Biotinylated Human ALCAM/CD166 Protein,Human,C-His-Avi,Expi293 |
Q13740 (W28-A526) |
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| Brain metastasis (BM) in non-small-cell lung cancer (NSCLC) has a very poor prognosis. Recent studies have demonstrated the importance of cell adhesion molecules in tumor metastasis. Elevated levels of ALCAM expression promote BM formation in NSCLC through increased tumor cell dissemination and interaction with the brain endothelial cells. Therefore, ALCAM could be targeted to reduce the occurrence of BM. | |||
| ALP8064 |
Biotinylated Human ANGPTL3/Angiopoietin-like 3 Protein,Human,C-His-Avi,Expi293 重组蛋白Biotinylated Human ANGPTL3/Angiopoietin-like 3 Protein,Human,C-His-Avi,Expi293 |
Q9Y5C1 (S17-K219) |
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| Adamas-life ® ANGPTL3 is a secreted glycoprotein that is structurally related to the angiopoietins. Mature human ANGPTL3 contains an N-terminal coiled coil domain and a C ‑ terminal fibrinogen-like domain. ANGPTL3 is expressed in the liver from early in development through adulthood. Acts in part as a hepatokine that is involved in regulation of lipid and glucose metabolism. Proposed to play a role in the trafficking of energy substrates to either storage or oxidative tissues in response to food intake. | |||
| ALP8071 |
Biotinylated Human ANGPT2/Angiopoietin-2 Protein,Human,N-His-Avi,Expi293 重组蛋白Biotinylated Human ANGPT2/Angiopoietin-2 Protein,Human,N-His-Avi,Expi293 |
O15123 -1 (K275-F496) |
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| Adamas-life ® Angiopoietin-2 (Ang-2; also ANGPT2) is a secreted glycoprotein that plays a complex role in angiogenesis and inflammation. Mature Ang-2 is 478 amino acids in length.Ang2 is widely expressed during development, but it is restricted postnatally to highly angiogenic tissues such as the placenta, ovaries, and uterus. It is particularly abundant in vascular endothelial cells (EC) where it is stored in intracellular Weibel Palade bodies. | |||
| ALP8104 |
Biotinylated Human BAFF/TNFSF13B/CD257 Trimer Protein,Human,N-His-Avi,Expi293 重组蛋白Biotinylated Human BAFF/TNFSF13B/CD257 Trimer Protein,Human,N-His-Avi,Expi293 |
Q9Y275-1 (A134-L285) |
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| Adamas-life ® B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B is a protein that in humans is encoded by the TNFSF13B gene.BAFF is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFF-R. | |||
| ALP8109 |
Biotinylated Human 4-1BB/TNFRSF9 Protein,Human,C-His-Avi,Expi293 重组蛋白Biotinylated Human 4-1BB/TNFRSF9 Protein,Human,C-His-Avi,Expi293 |
Q07011 (L24-Q186) |
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| 4-1BB, is also known as CD137, is a type 2 transmembrane glycoprotein receptor belonging to the TNF superfamily.CD137 can be expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, CD137 expression is found on dendritic cells, B cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation. | |||
| ALP8111 |
Biotinylated Human 4-1BB/TNFRSF9 Protein,Human,C-hFc-Avi,Expi293 重组蛋白Biotinylated Human 4-1BB/TNFRSF9 Protein,Human,C-hFc-Avi,Expi293 |
Q07011 (L24-Q186) |
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| 4-1BB, is also known as CD137, is a type 2 transmembrane glycoprotein receptor belonging to the TNF superfamily.CD137 can be expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, CD137 expression is found on dendritic cells, B cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation. | |||
| ALP8119 |
Biotinylated Human BCMA/TNFRSF17 Protein,Human,C-His-Avi,Expi293 重组蛋白Biotinylated Human BCMA/TNFRSF17 Protein,Human,C-His-Avi,Expi293 |
Q02223 (M1-A54) |
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| Adamas-life ® B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene.TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF). | |||
| ALP8122 |
Biotinylated Human BCMA/TNFRSF17 Trimer Protein,Human,C-His-Avi,Expi293 重组蛋白Biotinylated Human BCMA/TNFRSF17 Trimer Protein,Human,C-His-Avi,Expi293 |
Q02223 (M1-A54) |
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| Adamas-life ® B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene.TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF). | |||
| ALP8125 |
Biotinylated Mouse BCMA/TNFRSF17 Protein,Mouse,C-His-Avi,Expi293 重组蛋白Biotinylated Mouse BCMA/TNFRSF17 Protein,Mouse,C-His-Avi,Expi293 |
O88472 -1 (M1-T49) |
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| B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene.TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF). | |||
| ALP8131 |
Biotinylated Human B7-H4 Protein,Human,C-His-Avi,Expi293 重组蛋白Biotinylated Human B7-H4 Protein,Human,C-His-Avi,Expi293 |
Q7Z7D3 -1 (F29-A258) |
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| Adamas-life ® B7-H4, also known as B7x and B7S1, is a 50-80 kDa glycosylated member of the B7 family of immunomodulatory proteins.B7-H4 is up-regulated in several carcinomas in correlation with tumor progression and metastasis. A soluble form of B7-H4 is elevated in the serum of ovarian cancer, renal cell carcinoma, and rheumatoid arthritis patients, also in correlation with advanced disease status. | |||
| ALP6761 |
Biotinylated Human Activin A (INHBA)Protein, Human, C-Avi,HEK293 重组蛋白Biotinylated Human Activin A (INHBA)Protein, Human, C-Avi,HEK293 |
P08476 (G311-S426) |
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| INHBA 蛋白通过与激活素一起调节促卵泡激素的分泌，在调节垂体功能中发挥关键作用。其广泛的影响涵盖多种生理过程，包括激素分泌、生殖细胞发育、红细胞分化、胰岛素分泌、神经细胞存活、胚胎发育和骨骼生长，具体取决于独特的亚基组成。 | |||
| ALP8143 |
Biotinylated Human B7-H3 (4Ig) /B7-H3b Protein,Human,C-His-Avi,Expi293 重组蛋白Biotinylated Human B7-H3 (4Ig) /B7-H3b Protein,Human,C-His-Avi,Expi293 |
Q5ZPR3 -1 (G27-T461) |
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| Adamas-life ® B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig ‑ B7 ‑ H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. | |||
| ALP8145 |
Biotinylated Human B7-H2/ICOSLG Protein,Human,C-His-Avi,Expi293 重组蛋白Biotinylated Human B7-H2/ICOSLG Protein,Human,C-His-Avi,Expi293 |
O75144 -1 (D19-S258) |
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| Adamas-life ® B7-H2, also known as B7-related protein (B7RP1), ICOS Ligand, and CD275, is an approximately 60 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. B7-H2 is a ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. | |||
| ALP8146 |
Biotinylated Human B7-H6 Protein,Human,C-His-Avi,Expi293 重组蛋白Biotinylated Human B7-H6 Protein,Human,C-His-Avi,Expi293 |
Q68D85 (D25-S262) |
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| Adamas-life ® B7-H6 is a glycosylated member of the B7 family of immune co ‑ stimulatory proteins. which is a ligand for the NK cell activating receptor NKp30, was targeted to create a CAR that targets multiple tumor types. B7H6 is expressed on various primary human tumors, including leukemia, lymphoma and gastrointestinal stromal tumors, but it is not constitutively expressed on normal tissues. | |||
| ALP8149 |
Cynomolgus Serum Albumin Protein,Cynomolgus,C-His,Expi293 重组蛋白Cynomolgus Serum Albumin Protein,Cynomolgus,C-His,Expi293 |
A2V9Z4 (D25-A608) |
|
| Albumins are multifunctional proteins present in the blood serum of animals. They can bind and transport a wide variety of ligands which they accommodate due to their conformational flexibility. Serum albumins are highly conserved both in amino acid sequence and three-dimensional structure. Several mammalian and avian serum albumins (SAs) are also allergens. Sensitization to one of the SAs coupled with the high degree of conservation between SAs may result in cross-reactive antibodies in allergic individuals. | |||
| ALP8150 | P02768 -1 (D25-L609) |
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| Human serum albumin (HSA), the most prominent protein in plasma, binds different classes of ligands at multiple sites. HSA provides a depot for many compounds, affects pharmacokinetics of many drugs, holds some ligands in a strained orientation providing their metabolic modification, renders potential toxins harmLess transporting them to disposal sites, accounts for most of the antioxidant capacity of human serum, and acts as a NO-carrier. | |||
| ALP8151 |
Biotinylated Human Serum Albumin Protein,Human,C-His-Avi,Expi293 重组蛋白Biotinylated Human Serum Albumin Protein,Human,C-His-Avi,Expi293 |
P02768 -1 (D25-L609) |
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| Adamas-life ® Human serum albumin (HSA), the most prominent protein in plasma, binds different classes of ligands at multiple sites. HSA provides a depot for many compounds, affects pharmacokinetics of many drugs, holds some ligands in a strained orientation providing their metabolic modification, renders potential toxins harmless transporting them to disposal sites, accounts for most of the antioxidant capacity of human serum, and acts as a NO-carrier. | |||
| ALP8161 |
Biotinylated Human BTN1A1/Butyrophilin Protein,Human,C-His-Avi,Expi293 重组蛋白Biotinylated Human BTN1A1/Butyrophilin Protein,Human,C-His-Avi,Expi293 |
Q13410 (A27-R242) |
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| Butyrophilin 1A1 (BTN1A1) is one of the membrane proteins that surrounds LD, BTN1A1 plays an important role in regulating LD synthesis via a mechanism involving membrane phospholipid composition. | |||
