荧光标记蛋白利用GFP、mCherry等荧光蛋白与靶蛋白基因融合表达,在活细胞中可视化蛋白定位和动态。结合FRET、FRAP和超分辨成像技术,荧光标记蛋白已成为细胞生物学和神经科学的基础工具。荧光蛋白发色团由自身氨基酸自催化成熟,无需外源辅因子。
| 产品号 | 产品名称 | 蛋白编码 | 图片 |
|---|---|---|---|
| ALP22440 | P32970-1(L50-P193) |
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| CD70 is the ligand of CD27 in activated T and B lymphocytes, is an important cytokine in CD70-CD27 pathway involving with the generation and maintenance of T cell immunity. CD70 is a surface antigen, also shows antiviral activity and regulates viability of tumor cells and regulatory T cells. As for CD70 protein in human contains transmembrane domain and transmembrane helix, belonging to the tumor necrosis factor (TNF) family. | |||
| ALP23040 |
Recombinant FITC-Labeled Angiopoietin-2 Protein,Human,HEK293,N-His-Avi 重组蛋白FITC-Labeled Angiopoietin-2 Protein,Human,HEK293,N-His-Avi |
O15123-1(K275-F496) |
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| Angiopoietin-2 (ANGPT2) protein competes with ANGPT1 for TEK/TIE2 binding, modulates ANGPT1 signaling and induces TEK/TIE2 phosphorylation even in the absence of ANGPT1. In the absence of angiogenic stimulation, ANGPT2 disrupts cell-matrix contacts, potentially triggering endothelial cell apoptosis and vessel regression. | |||
| ALP23041 |
Recombinant FITC-Labeled Basigin/CD147 Protein,Human,HEK293,C-His |
P35613-2(A22-H205) |
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| Basigin/BSG proteins are critical for retinal maturation and development and function as retinal cell receptors for NXNL1, promoting the survival of retinal cone photoreceptors. | |||
| ALP23042 |
Recombinant FITC-Labeled CEACAM5 Protein,Human,HEK293,His,C-Avi |
P06731-1(K35-A685) |
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| CEACAM5 protein is a cell surface glycoprotein that cooperates with carcinoembryonic antigen-related molecules (such as CEACAM6) to participate in cell adhesion, intracellular signaling, and tumor progression. | |||
| ALP22336 |
Recombinant PE-labeled Glypican-3/GPC3 Protein,Human,HEK293,His |
P51654-1(Q25-H559) |
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| The Glypican-3 (GPC3) protein is a cell surface proteoglycan that plays complex regulatory roles in key signaling pathways critical to developmental processes. Through its GPI anchoring, GPC3 negatively regulates the Hedgehog signaling pathway by competing with the Hedgehog receptor PTC1 for binding to Hedgehog protein, leading to complex internalization and subsequent lysosomal degradation. | |||
| ALP22284 | P15391-1(P20-K291) |
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| The CD19 protein is a B cell antigen receptor coreceptor that enhances downstream signaling pathways, lowers the activation threshold, and helps B cells respond to antigens. It activates phosphatidylinositol 3-kinase and mobilizes intracellular Ca (2+). | |||
| ALP22337 |
Recombinant FITC-Labeled NKG2D/CD314 Protein,Human,HEK293,N-Fc-Flag |
P26718(F78-V216) |
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| The NKG2D/CD314 protein serves as a key activating and costimulatory receptor in immune surveillance, binding to multiple stress-inducing ligands on tumor and virus-infected cells. It plays a dual role by stimulating NK cells and enhancing T cell activation in CD8(+) T cell-mediated adaptive responses. | |||
| ALP22339 |
Recombinant FITC-Labeled CD276/B7-H3 4Ig/B7-H3b Protein,Human,HEK293,Fc 重组蛋白FITC-Labeled CD276/B7-H3 4Ig/B7-H3b Protein,Human,HEK293,Fc |
Q5ZPR3-1(G27-T461) |
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| CD276/B7-H3 protein can regulate T cell-mediated immune responses and act as a protective factor for tumor cells by inhibiting natural killer-mediated cell lysis . It also functions as a neuroblastoma cell marker, plays a role in acute and chronic transplant rejection, and modulates lymphocyte activity at mucosal surfaces. | |||
| ALP22389 | Q08722-1(Q19-P139) |
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| CD47 is an adhesion protein that regulates integrin signaling through G protein activation and serves as a receptor for thrombospondin THBS1, affecting signal transduction, cardiovascular homeostasis, inflammation, apoptosis , angiogenesis, self-renewal and Immunomodulatory. It regulates pulmonary endothelin EDN1 signaling, acts as a pressor in blood pressure regulation, and is critical for memory formation. | |||
| ALP22369 |
Recombinant FITC-labeled HER3 Protein,Human,HEK293,C-His-Avi |
P21860-1(S20-T643) |
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| HER3, a pivotal tyrosine-protein kinase, acts as a crucial cell receptor for neuregulins . Neuregulin-1 (NRG1) activation boosts tyrosine phosphorylation and interaction with p85 subunit of phosphatidylinositol 3-kinase. CSPG5 may also activate HER3. Its involvement in myeloid cell differentiation underscores HER3's vital role in essential cellular processes for normal development and function. | |||