无动物成分重组蛋白在不使用任何动物源原料的条件下表达纯化,消除BSE/TSE风险和批次间动物源变异,符合GMP级别细胞治疗和疫苗生产法规要求。表达系统包括大肠杆菌、酵母和无血清培养的哺乳动物细胞,在体外诊断原料和生物制药工艺中日益受到重视。
| 产品号 | 产品名称 | 蛋白编码 | 图片 |
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| ALP23302 | P22301(S19-N178) |
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| IL-10 protein is a major immunoregulatory cytokine with profound anti-inflammatory functions that limits excessive tissue destruction caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptors IL10RA and IL10RB, leading to JAK1- and STAT2-mediated phosphorylation of STAT3 , which translocates to the nucleus and drives the expression of anti-inflammatory mediators. This product is for cell culture use only. | |||
| ALP23338 | P05113-1(I20-S134) |
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| It also affects B-cells, inducing immunoglobulin production, growth, and differentiation. IL-5 Protein activates kinases like LYN , SYK , and JAK2 , which signal through RAS-MAPK and JAK-STAT5 pathways. It exists as a disulfide-linked homodimer and interacts with IL5RA and CSF2RB subunits. This product is for cell culture use only. | |||
| ALP23339 | P18893(S19-S178) |
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| IL-10 protein is a key immunomodulator that, by binding to its heterotetrameric receptors (IL10RA and IL10RB), activates JAK1 and STAT2 (the latter phosphorylates STAT3 ), thereby triggering potent anti-inflammatory effects. Phosphorylated STAT3 translocates to the nucleus and promotes the expression of anti-inflammatory mediators. This product is for cell culture use only. | |||
| ALP23374 | Q9NYY1-1(L25-E176) |
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| IL-20 protein is a proinflammatory cytokine secreted by monocytes and keratinocytes that is critical for immune responses, inflammation, hematopoiesis, and epidermal cell differentiation. It plays a key role in tissue remodeling, wound healing, and maintenance of epithelial homeostasis during infection . This product is for cell culture use only. | |||
| ALP23375 | P20809(P22-L199) |
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| IL-11 protein is a cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells, leading to increased platelet production. This product is for cell culture use only. | |||
| ALP23376 | P18510-1(R26-E177) |
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| IL-1RA/IL-1RN proteins are potent anti-inflammatory antagonists in the interleukin 1 family, specifically targeting the proinflammatory cytokines IL1B and IL1A. It protects against immune dysregulation and, crucially, prevents IL1 from triggering uncontrolled systemic inflammation in response to various innate stimulants, including pathogens. This product is for cell culture use only. | |||
| ALP23377 | P13500(Q24-T99) |
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| MCP-1/CCL2 (human) acts as a ligand for CCR2 , triggering a potent chemotactic response and intracellular calcium mobilization upon CCR2 binding. It specifically attracts monocytes and basophils while sparing neutrophils and eosinophils. This product is for cell culture use only. | |||
| ALP23378 | P35225(G35-N146) |
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| IL-13 Protein is a cytokine which is secreted by T helper type 2 (Th2) cells, CD4 cells, natural killer T cell, mast cells, basophils, eosinophils and nuocytes. IL-13 affects the morphology, growth, and surface antigen expression and phenotype of monocytes and elicits B cell proliferation. This product is for cell culture use only. | |||
| ALP23421 | O15520(L40-S208) |
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| KGF-2/FGF-10 proteins coordinate embryonic development, regulate cell proliferation and differentiation, and are indispensable in branching morphogenesis. This multifunctional protein may aid in wound healing. This product is for cell culture use only. | |||
| ALP23422 | P19876(A35-N107) |
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| The GRO-gama/CXCL3 Protein, acting as a CXCR2 ligand, induces chemotactic activity for neutrophils. It potentially influences inflammation through autocrine effects on endothelial cells. In vitro studies highlight the processed form GRO-gamma (5-73)'s fivefold increase in chemotactic activity for neutrophilic granulocytes, indicating a potential regulatory mechanism for neutrophil recruitment and function. This product is for cell culture use only. | |||
| ALP22736 | P32971(Q63-D234) |
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| CD30 ligand/TNFSF8 protein is a cytokine that specifically binds to TNFRSF8/CD30 and acts as a potent inducer of T cell proliferation. As a homotrimer, this ligand plays a crucial role in regulating T cell activation and growth, contributing to the dynamic coordination of immune responses. This product is for cell culture use only. | |||
| ALP22786 | P01135(V40-A89) |
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| TGF α/TGFA protein is a mitogenic polypeptide that binds to EGFR and acts synergistically with TGF β to promote anchorage-dependent cell proliferation. Its interaction with MAGI3, SDCBP , and the SNTA1 PDZ domain, especially with SDCBP , is critical for efficient cell surface targeting. This product is for cell culture use only. | |||
| ALP22882 | P01133-1(N971-R1023) |
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| EGF protein does not possess the conserved residue(s) necessary for propagating feature annotation. This product is for cell culture use only. | |||
| ALP22916 | P60568(A21-T153) |
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| IL-2 protein is mainly produced by activated CD4-positive helper T cells and plays an important role in immune response and tolerance. Binding to IL-2R induces downstream signaling through JAK1 and JAK3 phosphorylation, thereby activating various pathways, including STAT , PI3K , and MAPK. This product is for cell culture use only. | |||
| ALP22918 | P15692-4(A27-R191) |
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| VEGF165 Protein is a subtype of Vascular Endothelial Growth Factor A ( VEGF-A ). VEGF-A is a key member of the VEGF family of cytokines that can promote neovascularization and increase vascular permeability. | |||
| ALP23046 | P48023-1(Q130-L281) |
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| Fas Ligand (CD178; APTL) is a ligand to TNFRSF6/FAS/CD95 , transduces the apoptotic signal to regulate cytotoxic T-cell-mediated apoptosis , natural killer cell-mediated apoptosis and in T-cell development. Human Fas Ligand exhibits 4 isoforms, the soluble form (130-281 a.a.) of which plays an important role in the activation-induced cell death (AICD) of T lymphocytes Jurkat cells. However the membrane-bound isoform could be responsible for its inflammatory activity. | |||
| ALP23462 | Q9JHH5(F22-M100) |
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| The CXCL11 protein selectively attracts interleukin-activated T cells and induces calcium release in these cells. Its binding to CXCR3 suggests a complex role in T cell chemotaxis and may be important in CNS diseases involving T cell recruitment. This product is for cell culture use only. | |||
| ALP23463 | Q9JLA2(M1-H160) |
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| IL-36 alpha protein binds to the IL1RL2/IL-36R receptor and activates the NF-kappa-B and MAPK signaling pathways. This product is for cell culture use only. | |||
| ALP23465 | Q9GZX6(A34-I179) |
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| Animal-derived-free IL-22 protein is a cytokine that regulates tissue responses during inflammation and contributes to epithelial cell regeneration to maintain barrier function and prevent tissue damage. This product is for cell culture use only. | |||
| ALP23466 | Q8BSU2(N27-W201) |
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| The CXCL16 protein has multiple functions, inducing chemotactic responses and initiating calcium mobilization. As a ligand, it binds to CXCR6/Bonzo and promotes cell signaling. This product is for cell culture use only. | |||