一抗直接识别靶抗原特定表位,分为单克隆(单一表位,特异性和批次一致性高)和多克隆(多个表位,灵敏度高)。种属来源决定配套二抗选择。广泛用于WB、IHC、IF、ELISA和流式,经敲除对照验证的一抗可靠性更高。
| 产品号 | 产品名称 | 应用 | 图片 |
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| ALP12935 | 用于 Western Blot、免疫组化、免疫荧光、免疫沉淀等免疫学实验中 TATA Box Binding Protein (9D1) 蛋白的特异性检测、表达水平分析与亚细胞定位研究。 |
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| Adamas-life® As one of the few proteins in the preinitation complex that binds DNA in a sequence-specific manner, it helps position RNA polymerase II over the transcription start site of the gene. However, it is estimated that only 10-20% of human promoters have TATA boxes. Therefore, TBP is probably not the only protein involved in positioning RNA polymerase II. This protein is not suitable for samples where the nuclear envelope has been removed. | |||
| ALP12937 | 用于 Western Blot、免疫组化、免疫荧光、免疫沉淀等免疫学实验中 Acetyl-Alpha Tubulin (Lys40) (6B5) 蛋白的特异性检测、表达水平分析与亚细胞定位研究。 |
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| Adamas-life® TUBA1A Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. | |||
| ALP12940 | 用于 Western Blot、免疫组化、免疫荧光、免疫沉淀等免疫学实验中 PRMT6 蛋白的特异性检测、表达水平分析与亚细胞定位研究。 |
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| Adamas-life® Protein arginine N-methyltransferases, such as PRMT6, catalyze the sequential transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. | |||
| ALP12946 | 用于 Western Blot、免疫组化、免疫荧光、免疫沉淀等免疫学实验中 Cytokeratin 18 蛋白的特异性检测、表达水平分析与亚细胞定位研究。 |
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| Adamas-life® KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. | |||
| ALP12949 | 用于 Western Blot、免疫组化、免疫荧光、免疫沉淀等免疫学实验中 Pyruvate Dehydrogenase E2 蛋白的特异性检测、表达水平分析与亚细胞定位研究。 |
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| Adamas-life® The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). | |||
| ALP12952 | 用于 Western Blot、免疫组化、免疫荧光、免疫沉淀等免疫学实验中 Nrf1 蛋白的特异性检测、表达水平分析与亚细胞定位研究。 |
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| Adamas-life® Transcription factor that activates the expression of the EIF2S1 (EIF2- alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. | |||
| ALP12954 | 用于 Western Blot、免疫组化、免疫荧光、免疫沉淀等免疫学实验中 Annexin A1 蛋白的特异性检测、表达水平分析与亚细胞定位研究。 |
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| Adamas-life® Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process。Has anti-inflammatory activity (PubMed:8425544)。Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades (PubMed:15187149, PubMed:25664854)。Contributes to the adaptive immune response by enhancing signaling cascades that are triggered by T-cell activation, regulates differentiation and proliferation of activated T-cells (PubMed:17008549)。 | |||
| ALP13295 | 用于 Western Blot、免疫组化、免疫荧光、免疫沉淀等免疫学实验中 HIV 1 p24 (1F8) 蛋白的特异性检测、表达水平分析与亚细胞定位研究。 |
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| Adamas-life® HIV-1 p24 Monoclonal Antibody: The human immunodeficiency virus type 1 (HIV-1) particle consists of an envelope, a core and the region between the two termed matrix. The HIV-1 Gag protein is a late structural protein that contains four proteins: matrix (p17), capsid (p24), nucleocapsid (p7) and the p6 protein. The p24 constitutes the major core component of the virus and shows high degree of sequence conservation among HIV isolates. The Gag p24 has been used as an integral part of multicomponent HIV-1 vaccines. | |||
| ALP13299 | 用于 Western Blot、免疫组化、免疫荧光、免疫沉淀等免疫学实验中 Clostridium Difficile Toxin B (6G11) 蛋白的特异性检测、表达水平分析与亚细胞定位研究。 |
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| Adamas-life® Precursor of a cytotoxin that targets and disrupts the colonic epithelium, inducing the host inflammatory and innate immune responses and resulting in diarrhea and pseudomembranous colitis. | |||
| ALP13300 | 用于 Western Blot、免疫组化、免疫荧光、免疫沉淀等免疫学实验中 Clostridium Difficile Toxin B (7D7) 蛋白的特异性检测、表达水平分析与亚细胞定位研究。 |
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| Adamas-life® Precursor of a cytotoxin that targets and disrupts the colonic epithelium, inducing the host inflammatory and innate immune responses and resulting in diarrhea and pseudomembranous colitis. | |||
| ALP13302 | 用于 Western Blot、免疫组化、免疫荧光、免疫沉淀等免疫学实验中 Clostridium Difficile Toxin B (7G1) 蛋白的特异性检测、表达水平分析与亚细胞定位研究。 |
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| Adamas-life® Precursor of a cytotoxin that targets and disrupts the colonic epithelium, inducing the host inflammatory and innate immune responses and resulting in diarrhea and pseudomembranous colitis. | |||
| ALP13305 | 用于 Western Blot、免疫组化、免疫荧光、免疫沉淀等免疫学实验中 Hepatitis B Surface gen (HBsAg) (7F7) 蛋白的特异性检测、表达水平分析与亚细胞定位研究。 |
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| Adamas-life® The hepatitis B surface antigen (HBsAg) is most frequently used to screen for the presence of this infection. It is the first detectable viral antigen to appear during infection. However, early in an infection, this antigen may not be present and it may be undetectable later in the infection as it is being cleared by the host. | |||
| ALP13308 | 用于 Western Blot、免疫组化、免疫荧光、免疫沉淀等免疫学实验中 Tissue Factor Pathway Inhibitor 蛋白的特异性检测、表达水平分析与亚细胞定位研究。 |
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| Adamas-life® Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma. | |||
| ALP13310 | 用于 Western Blot、免疫组化、免疫荧光、免疫沉淀等免疫学实验中 CDC25C 蛋白的特异性检测、表达水平分析与亚细胞定位研究。 |
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| Adamas-life® This gene encodes a conserved protein that plays a key role in the regulation of cell division. The encoded protein directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It also suppresses p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described. | |||
| ALP13660 | 用于 Western Blot、ELISA 等免疫学实验中 T2 蛋白的一步法直接检测,无需二抗孵育即可完成显色或化学发光成像。 |
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| Adamas-life® This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. | |||
| ALP13663 | 用于 Western Blot、免疫组化、免疫荧光、免疫沉淀等免疫学实验中 C1QA 蛋白的特异性检测、表达水平分析与亚细胞定位研究。 |
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| Adamas-life® C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. | |||
| ALP13668 | 用于 Western Blot、免疫组化、免疫荧光、免疫沉淀等免疫学实验中 Ceruloplasmin 蛋白的特异性检测、表达水平分析与亚细胞定位研究。 |
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| Adamas-life® Ceruloplasmin is a blue, copper-binding (6-7 atoms per molecule) glycoprotein. It has ferroxidase activity oxidizing Fe(2+) to Fe(3+) without releasing radical oxygen species. It is involved in iron transport across the cell membrane. | |||
| ALP13671 | 用于 Western Blot、免疫组化、免疫荧光、免疫沉淀等免疫学实验中 LAP3 蛋白的特异性检测、表达水平分析与亚细胞定位研究。 |
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| Adamas-life® Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. | |||
| ALP13673 | 用于 Western Blot、免疫组化、免疫荧光、免疫沉淀等免疫学实验中 Fetuin B 蛋白的特异性检测、表达水平分析与亚细胞定位研究。 |
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| Adamas-life® Protease inhibitor required for egg fertilization. Required to prevent premature zona pellucida hardening before fertilization, probably by inhibiting the protease activity of ASTL, a protease that mediates the cleavage of ZP2 and triggers zona pellucida hardening (By similarity). | |||
| ALP13677 | 用于 Western Blot、免疫组化、免疫荧光等免疫学实验中 Vimentin (Ser72) 磷酸化修饰水平的特异性检测,适用于相关信号通路激活状态的研究。 |
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| Adamas-life® Vimentin an intermediate filament protein. Intermediate filament proteins are expressed in a tissue-specific manner. Desmin is the subunit specific for muscle and vimentin the subunit specific for mesenchymal tissue. | |||