受体丝氨酸/苏氨酸激酶是一类跨膜蛋白，通过磷酸化底物丝氨酸或苏氨酸残基，介导细胞外信号向胞内传递，调控生长、发育等过程。
| 产品号 | 产品名称 | 蛋白编码 | 图片 |
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| ALP9217 | Q16671-1(Pro18-Ser144) |
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| The aim of the current study was to explore whether anti-Müllerian hormone receptor II (AMHRII) genetic variants influence the hormonal profile and the ovarian response to standard gonadotropin stimulation of women undergoing medically assisted reproduction. Three hundred in vitro fertilization or intracytoplasmic sperm injection patients constituted the study population, while 300 women with at least one spontaneous pregnancy participated as controls. | |||
| ALP23140 | P38438(I24-Q166) |
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| TGFBR2 is a transmembrane kinase that forms the TGF-β receptor complex with TGFBR1 and regulates various processes. Upon binding to cytokines, this complex activates TGFBR2, initiating SMAD-dependent signaling through phosphorylation of TGFBR1, SMAD2 , and SMAD4 . | |||
| ALP22433 |
Recombinant ACVR2A/Activin RIIA Protein,Human/Cynomolgus,HEK293,C-Fc 重组蛋白ACVR2A/Activin RIIA Protein,Human/Cynomolgus,HEK293,C-Fc |
P27037-1/G7PKJ4(A20-P135) |
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| ACVR2A , also known as Activin RIIA, is an activin type II receptor. On ligand binding, ACVR2A can forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. ACVR2A is a receptor for Activin A , Activin B and Inhibin A. | |||
| ALP22288 | Q13705-1(S19-T134) |
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| ACVR2B is a type II member of the TGF-β family of receptor Serine/Threonine kinases . ACVR2B binds to activins and growth differentiation factors (GDF), which in turn activate type I receptors, activating downstream molecule SMAD2/3. | |||
| ALP25731 | Q61288(D23-P119) |
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| ALK-1, also known as ACVRL1, is a type I receptor for TGF-β superfamily with 2 ligands, BMP9 and BMP10. | |||
| ALP25738 | Q61271/NP_031421.1(L32-E126) |
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| Activin RIB, also known as activin receptor type-1B (ACVR1B) or ALK-4, is a type I transmembrane serine/threonine kinase receptor that is part of the TGF-β receptor superfamily. Activin binds to a type II activin receptor (ACVR2or ACVR2B ) and then recruits ACVR1B. | |||
| ALP25775 |
Recombinant Activin RIB/ALK-4 Protein,Rhesus Macaque,HEK293,C-Fc |
I2CYX8/NP_001252559.1(R27-E126) |
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| Activin RIB, also known as activin receptor type-1B (ACVR1B) or ALK-4, is a type I transmembrane serine/threonine kinase receptor that is part of the TGF-β receptor superfamily. Activin binds to a type II activin receptor (ACVR2or ACVR2B ) and then recruits ACVR1B. | |||
| ALP25763 | F7A9J8(D23-E123) |
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| Activin A receptor, type I (ACVR1), also known as ALK-2, is a bone morphogenetic protein (BMP) type I receptor. ACVR1 is involved in a wide variety of biological processes, including bone, heart, cartilage, nervous, and reproductive system development and regulation. | |||
| ALP25769 | A0A2K5VZP2(G25-E113) |
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| ALK-7 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived ALK-7 protein, expressed by HEK293 , with C-His tag. | |||
| ALP25771 | Q8K348(L26-E113) |
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| ALK-7 Protein, Mouse (HEK293, His) is the recombinant mouse-derived ALK-7 protein, expressed by HEK293 , with C-8*His tag. | |||
| ALP24820 | Q64729(L30-E125) |
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| TGFBR1 is a transmembrane kinase that cooperates with TGFBR2 to form the TGF-β receptor complex.This complex is activated by cytokines and regulates a variety of processes, including cell cycle arrest, mesenchymal cell control, wound healing, and carcinogenesis. | |||
| ALP24846 | P36895(Q24-R152) |
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| BMPR1A/ALK-3 protein mediates iron metabolism factor hepcidin expression, interacts with GDF5/6 to regulate chondrocyte differentiation and adipogenesis. BMPR1A-ID2/ZEB1-TGFBR2 signaling axis could serve as a potentia target for pulmonary arterial hypertension (PAH) and other endothelial-mesenchymal transition (EndoMT)-related vascular disorders. Mouse BMPR1A/ALK-3 has a full length of 532 a.a., with a motif (107-109 a.a.) mediating specificity for BMP ligand. | |||
| ALP25083 | P36896(S24-E126) |
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| Activin RIB, also known as activin receptor type-1B (ACVR1B) or ALK-4, is a type I transmembrane serine/threonine kinase receptor that is part of the TGF-β receptor superfamily. Activin binds to a type II activin receptor (ACVR2or ACVR2B ) and then recruits ACVR1B. | |||
| ALP25501 | P80201(M21-E123) |
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| Activin A receptor, type I (ACVR1), also known as ALK-2, is a bone morphogenetic protein (BMP) type I receptor. ACVR1 is involved in a wide variety of biological processes, including bone, heart, cartilage, nervous, and reproductive system development and regulation. | |||
| ALP25227 | Q8K592(Q16-M147) |
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| The AMHR2/MISRII protein assembles receptor complexes with two type II and two type I transmembrane serine/threonine kinases upon ligand binding. Type II receptors initiate signaling cascades by phosphorylating and activating type I receptors, which undergo autophosphorylation. | |||
| ALP24264 | EHH16502.1(S28-T118) |
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| ACVR2B is a type II member of the TGF-β family of receptor Serine/Threonine kinases . ACVR2B binds to activins and growth differentiation factors (GDF), which in turn activate type I receptors, activating downstream molecule SMAD2/3. | |||
| ALP24265 |
Recombinant TGFBR2/TGF-beta RII Protein,Rhesus Macaque,HEK293,C-Fc |
NP_001248080.1(I24-D159) |
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| TGFBR2/TGF-beta RII Protein collaborates with TGFBR1 to form a dedicated receptor for TGFB1, TGFB2, and TGFB3. It serves as a signal transducer, orchestrating diverse physiological and pathological processes, including cell cycle regulation, mesenchymal cell dynamics, wound healing, matrix production, immunosuppression, and carcinogenesis. Upon cytokine binding, the receptor complex activates TGFBR1 through TGFBR2 phosphorylation, initiating the canonical SMAD-dependent TGF-beta signaling cascade. Additionally, TGFBR2 participates in non-canonical, SMAD-independent pathways. | |||
| ALP24350 | Q62312-2(I24-D159) |
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| TGF-beta receptor type-2 is the ligand-binding receptor for all members of the TGF-β family. | |||
| ALP24421 |
Recombinant Biotinylated ACVR2A/Activin RIIA Protein,Human/Cynomolgus,HEK293,His,C-Avi 重组蛋白Biotinylated ACVR2A/Activin RIIA Protein,Human/Cynomolgus,HEK293,His,C-Avi |
P27037-1/G7PKJ4(A20-P135) |
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| ACVR2A/Activin RIIA Protein, Human/Cynomolgus (Biotinylated, HEK293, His, Avi) is the recombinant human-derived ACVR2A/Activin RIIA protein, expressed by HEK293 , with C-Avi & C-His tag. | |||
| ALP24604 | Q04771(M21-V124) |
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| Activin A receptor, type I (ACVR1), also known as ALK-2, is a bone morphogenetic protein (BMP) type I receptor. ACVR1 is involved in a wide variety of biological processes, including bone, heart, cartilage, nervous, and reproductive system development and regulation. | |||
