白细胞免疫球蛋白样受体是一类主要表达于免疫细胞表面的跨膜蛋白，通过识别自身或外来配体调节免疫应答，在抗感染和自身免疫中发挥关键作用。
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| 产品号 | 产品名称 | 蛋白编码 | 图片 |
|---|---|---|---|
| ALP6828 | Q6PI73 -1 (G24-N447) |
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| LILRA6/CD85b/ILT-8蛋白作为I类MHC抗原的受体，在免疫识别和调节中发挥着至关重要的作用。它与 I 类 MHC 分子的相互作用已被证明参与监测和潜在调节免疫反应。 | |||
| ALP9596 |
Recombinant Cynomolgus LILRA6/CD85b/ILT8 Protein,Cynomolgus,C-His,Expi293 重组蛋白Cynomolgus LILRA6/CD85b/ILT8 Protein,Cynomolgus,C-His,Expi293 |
A0A2K5VN04(Gly41-His474) |
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| The LILRs are a family of receptors that regulate the activities of myelomonocytic cells. Specific allelic variants of two related members of the LILR family, LILRB3 and LILRA6, interact with a ligand exposed on necrotic glandular epithelial cells. The extracellular domains of LILRB3 and LILRA6 are very similar and their genes are highly polymorphic. | |||
| ALP9586 |
Recombinant Human LILRB4/CD85k/ILT3 Domain 1 Protein,Human,C-His-Avi,Expi293 重组蛋白Human LILRB4/CD85k/ILT3 Domain 1 Protein,Human,C-His-Avi,Expi293 |
AAH26309.1(Gln22-Thr118) |
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| LILRB4,also known as CD85k and LIR-5, ILT-3, is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT-3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM).LILRB4 is receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. | |||
| ALP8757 |
Recombinant Human LILRA6/CD85b/ILT8 Protein,Human,C-His-Avi,Expi293 |
Q6PI73-1(Gly24-Asn447) |
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| The LILRs are a family of receptors that regulate the activities of myelomonocytic cells. Specific allelic variants of two related members of the LILR family, LILRB3 and LILRA6, interact with a ligand exposed on necrotic glandular epithelial cells. The extracellular domains of LILRB3 and LILRA6 are very similar and their genes are highly polymorphic. | |||
| ALP8761 |
Recombinant Human LILRB2/CD85d/ILT4 Protein,Human,C-His-Avi,Expi293 |
AAL36991.1(Gln22-His458) |
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| The immunoglobulin-like transcript (ILT) comprise a family of activating and inhibitory type immunoreceptors whose genes are located in the same locus that encodes killer cell Ig-like receptors (KIR). ILT4, also known as LIR-2 and LILRB2, is a type I transmembrane protein expressed primarily on monocytes and dendritic cells (DC). LILRB2 is a receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. | |||
| ALP8763 |
Recombinant Human LILRB3/CD85a/ILT5 Protein,Human,C-His-Avi,Expi293 |
O75022-1(Gly24-Glu443) |
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| Leukocyte immunoglobulin-like receptor subfamily B (LILRB3), also known as ILT5, LIR3, and CD85a, is an immunoglobulin superfamily member that is involved in immune regulation. Subfamily B members have cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs) that inhibit signaling events via phosphatase SHP-1.LILRB3 may act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. | |||
| ALP8765 |
Recombinant Human LILRB4/CD85k/ILT3 Protein,Human,C-His-Avi,Expi293 |
Q8NHJ6-1(Gln22-His257) |
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| LILRB4,also known as CD85k and LIR-5, ILT-3, is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT-3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM).LILRB4 is receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. | |||
| ALP8767 |
Recombinant Human LILRB5/CD85c/LIR-8 Protein,Human,C-His-Avi,Expi293 重组蛋白Human LILRB5/CD85c/LIR-8 Protein,Human,C-His-Avi,Expi293 |
O75023-1(Arg18-His456) |
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| LILRB5, also known as CD85c andLIR-8, belongs to a family of transmembrane glycoproteins that negatively regulate immune cell activation. Mature human LIR-8 consists of a 435 amino acid (aa) extracellular domain with four Ig-like domains, a 21 aa transmembrane segment, and a 111 aa cytoplasmic domain with two immunoreceptor tyrosine-based inhibitory motifs (ITIM). LILRB5 may act as receptor for class I MHC antigens. | |||
| ALP8769 |
Recombinant Mouse LILRB4/CD85k/ILT3 Protein,Mouse,C-His,Expi293 |
Q64281-1(Gly24-Lys238) |
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| LILRB4,also known as CD85k and LIR-5, ILT3, is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM).LILRB4 is receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. | |||
| ALP8734 |
Recombinant Cynomolgus LILRB2/CD85d/ILT4 Protein,Cynomolgus,C-His,Expi293 重组蛋白Cynomolgus LILRB2/CD85d/ILT4 Protein,Cynomolgus,C-His,Expi293 |
XM_015441717(Gly24-Arg457) |
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| The immunoglobulin-like transcript (ILT) comprise a family of activating and inhibitory type immunoreceptors whose genes are located in the same locus that encodes killer cell Ig-like receptors (KIR). ILT4, also known as LIR-2 and LILRB2, is a type I transmembrane protein expressed primarily on monocytes and dendritic cells (DC). LILRB2 is a receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. | |||
| ALP8735 |
Recombinant Cynomolgus LILRB4/CD85k/ILT3 Protein,Cynomolgus,C-His,Expi293 重组蛋白Cynomolgus LILRB4/CD85k/ILT3 Protein,Cynomolgus,C-His,Expi293 |
XP_015297198.1(Gln22-Glu259) |
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| LILRB4,also known as CD85k and LIR-5, ILT3, is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM).LILRB4 is receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. | |||
| ALP8737 |
Recombinant Rhesus macaque LILRB1/CD85j/ILT2 Protein,Rhesus macaque,C-hFc,Expi293 重组蛋白Rhesus macaque LILRB1/CD85j/ILT2 Protein,Rhesus macaque,C-hFc,Expi293 |
F7H3G7(Ser17-His456) |
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| LILRB1, also known as CD85j and ILT2, is a 110 kDa transmembrane glycoprotein in the LILR immunoregulatory protein family. Mature human LILRB1 consists of a 438 amino acid (aa) extracellular domain (ECD) with 4 tandem Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 4 inhibitory ITIM motifs.LILRB1 is a receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. Receptor for H301/UL18, a human cytomegalovirus class I MHC homolog. Ligand binding results in inhibitory signals and down-regulation of the immune response. | |||
| ALP8740 |
Recombinant Human LILRB2/CD85d/ILT4 Domain1&2 Protein,Human,C-His,Expi293 重组蛋白Human LILRB2/CD85d/ILT4 Domain1&2 Protein,Human,C-His,Expi293 |
Q8N423-1(Gln22-Val229) |
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| The immunoglobulin-like transcript (ILT) comprise a family of activating and inhibitory type immunoreceptors whose genes are located in the same locus that encodes killer cell Ig-like receptors (KIR). ILT4, also known as LIR-2 and LILRB2, is a type I transmembrane protein expressed primarily on monocytes and dendritic cells (DC). LILRB2 is a receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. | |||
| ALP8743 |
Recombinant Human LILRB2/CD85d/ILT4 Protein,Human,C-hFc,Expi293 |
Q8N423-1(Gln22-His458) |
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| The immunoglobulin-like transcript (ILT) comprise a family of activating and inhibitory type immunoreceptors whose genes are located in the same locus that encodes killer cell Ig-like receptors (KIR). ILT4, also known as LIR-2 and LILRB2, is a type I transmembrane protein expressed primarily on monocytes and dendritic cells (DC). LILRB2 is a receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. | |||
| ALP8744 |
Recombinant Human LILRB4/CD85k/ILT3 Protein,Human,C-hFc,Expi293 |
Q8NHJ6-1(Gln22-Arg256) |
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| LILRB4,also known as CD85k and LIR-5, ILT3, is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM).LILRB4 is receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. | |||
| ALP8746 |
Recombinant Human LILRB2/CD85d/ILT4 Protein,Human,C-mFc,Expi293 |
AAL36991.1(Gln22-His458) |
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| The immunoglobulin-like transcript (ILT) comprise a family of activating and inhibitory type immunoreceptors whose genes are located in the same locus that encodes killer cell Ig-like receptors (KIR). ILT4, also known as LIR-2 and LILRB2, is a type I transmembrane protein expressed primarily on monocytes and dendritic cells (DC). LILRB2 is a receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. | |||
| ALP8749 |
Recombinant Human LILRA2/CD85h/ILT1 Protein,Human,C-His-Avi,Expi293 |
Q8N149-1(Gly24-Asn449) |
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| LILRA2, also known as ILT1, CD85h, and LIR7, is an approximately 70 kDa variably glycosylated transmembrane protein that regulates immune cell activation. Mature human LILRA2 consists of a 426 amino acid (aa) extracellular domain (ECD) with 4 Ig-like domains, a 21 aa transmembrane segment, and a 13 aa cytoplasmic tail. LILRA2 is part of the innate immune responses against microbial infection. | |||
| ALP24981 | AAI04994.1(G24-E443) |
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| LILRB3/CD85a protein, as a receptor for class I MHC antigens, plays an indispensable role in immune recognition. Activation of LILRB3 occurs through binding to immune receptors such as FCGR2B and B cell receptors, resulting in downregulation of antigen-induced B cell activation. | |||
| ALP25643 | Q8NHJ6-1(Q22-E259) |
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| The LILRB4/CD85k/ILT3 protein is a key inhibitory receptor that plays a key role in immune regulation and tolerance. As a receptor for FN1, apolipoprotein APOE, and ALCAM/CD166 , it inhibits receptor-mediated phosphorylation, intracellular calcium mobilization, and FCGR1A/CD64-mediated monocyte activation, thereby reducing TNF production. | |||
| ALP25225 |
Recombinant LILRB2/CD85d/ILT-4 Protein,Cynomolgus,HEK293,C-Fc |
XP_015297203.1(G24-R457) |
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| The LILRB2/CD85d/ILT-4 protein is a receptor for class I MHC antigens and can recognize multiple HLA alleles. It crucially downregulates the immune response and builds tolerance. | |||
