细胞因子受体是位于细胞膜上的蛋白质，能特异性结合细胞因子，激活细胞内信号通路，调节免疫和炎症反应。
| 产品号 | 产品名称 | 蛋白编码 | 图片 |
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| ALP24766 | Q63953/NP_032364(A20-V243) |
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| Recombinant IFN-gamma R2 Protein, expressed in HEK293 cells with C-terminal His tag. | |||
| ALP24810 | P38445(S19-T137) |
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| RIIB/ACVR2B Protein, Rat (HEK293, His) is the recombinant rat-derived RIIB/ACVR2B protein, expressed by HEK293 , with C-His tag. | |||
| ALP24813 | P38444(A20-P135) |
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| ACVR2A/Activin RIIA Protein, Rat (HEK293, His) is the recombinant rat-derived RIIA/ACVR2A protein, expressed by HEK293 , with C-His tag. | |||
| ALP24820 | Q64729(L30-E125) |
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| TGFBR1 is a transmembrane kinase that cooperates with TGFBR2 to form the TGF-β receptor complex.This complex is activated by cytokines and regulates a variety of processes, including cell cycle arrest, mesenchymal cell control, wound healing, and carcinogenesis. | |||
| ALP24846 | P36895(Q24-R152) |
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| BMPR1A/ALK-3 protein mediates iron metabolism factor hepcidin expression, interacts with GDF5/6 to regulate chondrocyte differentiation and adipogenesis. BMPR1A-ID2/ZEB1-TGFBR2 signaling axis could serve as a potentia target for pulmonary arterial hypertension (PAH) and other endothelial-mesenchymal transition (EndoMT)-related vascular disorders. Mouse BMPR1A/ALK-3 has a full length of 532 a.a., with a motif (107-109 a.a.) mediating specificity for BMP ligand. | |||
| ALP24944 | Q5U2S8(S28-A218) |
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| TNFRSF3/LTBR Protein, Rat (HEK293, His) is a cell surface receptor for apoptotic and cytokine-released lymphotoxins involved in activation of gene transcription programs and cell death, and is important in immune development and host defense. | |||
| ALP25317 | NP_075594.1(R22-E285) |
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| FGFR-1 beta is a member of the FGFR family that interacts with fibroblast growth factors and regulates mitosis and differentiation. It specifically binds acidic and basic fibroblast growth factors and is involved in limb induction. | |||
| ALP25836 | P35917(Y25-E775) |
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| VEGFR-3/FLT4 proteins are tyrosine protein kinase receptors for VEGFC and VEGFD and are critical in adult lymphangiogenesis and embryonic vascular development. It promotes endothelial cell function, angiogenesis, and forms a positive feedback loop that increases VEGFC production. | |||
| ALP25124 | XP_001105270(A23-K745) |
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| TIE-2 Protein, a tyrosine-protein kinase, acts as a cell-surface receptor for ANGPT1, ANGPT2, and ANGPT4, exerting comprehensive control over angiogenesis, endothelial cell behavior, and vascular stability. It regulates diverse processes, including endothelial cell survival, proliferation, migration, adhesion, and actin cytoskeleton reorganization, while also playing a crucial role in maintaining vascular quiescence and preventing the leakage of pro-inflammatory plasma proteins and leukocytes from blood vessels. | |||
| ALP25512 | D4ACA7(A64-E554) |
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| CSF1R Protein is a cell surface receptor with high a affinity for a variety of polypeptide growth factors, cytokines, and hormones . CSF1R Protein participate in PLCG2/PKA/UCP2 signaling pathway to reduce oxidative stress and neuronal apoptosis in rat models with neonatal HIE. The blocking of the CSF1R signal is associated with tumorigenesis. | |||
| ALP22307 |
Recombinant Biotinylated EGFR Protein,Human,621a.a,HEK293,C-His |
P00533-1(L25-S645) |
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| The EGFR protein is a receptor tyrosine kinase that can bind to a variety of ligands, such as EGF , TGFA, AREG, epigen , BTC, epiregulin , and HBEGF, to initiate signaling cascades that mediate cellular responses. This involves receptor dimerization, autophosphorylation and recruitment of adapter proteins such as GRB2, activating downstream pathways such as RAS-RAF-MEK-ERK, PI3-kinase-AKT, PLCgamma-PKC and STAT . | |||
| ALP22308 | P35918(A20-E762) |
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| VEGFR-2 protein is an important tyrosine protein kinase receptor.As a cell surface receptor for VEGFA, VEGFC and VEGFD, it plays an important role in the regulation of angiogenesis, vascular development, permeability and embryonic hematopoiesis.It actively promotes endothelial cell proliferation, survival, migration, differentiation, and actin cytoskeletal reorganization. | |||
| ALP22341 | P24394-1(M26-H232) |
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| IL-4R alpha is a subunit alpha shared by IL-4 and IL-13 receptors, found in leukocytes originally. IL-4R alpha couples to the JAK1/2/3-STAT6 pathway and involves in promoting Th2 differentiation. Soluble IL-4R (sIL-4R) inhibits IL4-mediated cell proliferation and IL-5 up-regulation by T-cells. | |||
| ALP23319 | Q00560/NP_034690(Q23-E617) |
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| Glycoprotein 130 (gp130) is a trans-membrane protein, is the common signal-transducing receptor subunit of the interleukin-6 ( IL-6 ) family. gp130 inhibits the cell growth and migration, decreases the STAT3 phosphorylation induced by IL-6 , and decreases IL-6-induced increase of Ki67. gp130 shows anti-tumor, anti-inflammation and anti-nociceptive activity. | |||
| ALP23320 |
Recombinant IL2RB-IL2RG Heterodimer Protein,Human,HEK293,C-Fc |
P14784(A27-T240) |
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| IL-2R beta (CD122) and IL-2Rγ (CD132), type Ⅰ cytokine receptors expressed on T lymphocytes, are receptors for IL-2 (K d : 1 nM for IL-2R beta approximately). IL-2R beta mediates T cell immune responses. IL-2Rγ mediates inflammatory response IL-2Rβ and IL-2Rγ heterodimer binds to IL-2 with intermediate affinity. | |||
| ALP22411 | P08581-1(E25-T932) |
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| The HGFR protein is a receptor tyrosine kinase that transduces signals by binding to hepatocyte growth factor/HGF ligand. It regulates proliferation, scattering, morphogenesis, and cell survival. | |||
| ALP25037 | Q62312-2(I24-D159) |
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| TGFBR2/TGF-beta RII Protein, Mouse (HEK293, Fc), a fragment of transforming growth factor-beta receptor type 2 (TβRII), with a 6His tag at the C-terminus. | |||
| ALP25046 | F6V1W6(Q26-D173) |
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| Fas receptor is a cell surface death receptor , can bind to Fas ligand to form death-inducing signaling complexes, such as Fas associated death domain proteins (FADD). Fas receptor participates in the caspase cascade and regulate the activation of JNK and p38-K downstream. It is also involved in the signaling cascade of ERK/JNK MAPKs, activating MAPK3/ERK1, MAPK8/JNK and NF-κB , which has been implicated in the pathogenesis of various malignant tumors and immune system diseases. Macaca mulatta Fas receptor contain a death domain (228-312 a.a.) that plays a key role in regulating programmed death. | |||
| ALP25047 | E9Q5C3/AAA39377.1(R22-E263) |
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| FGFR-2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived FGFR-2 , expressed by HEK293 , with C-6*His labeled tag. | |||
| ALP25049 |
Recombinant FGFR-3 Protein,Cynomolgus/Rhesus Macaque,HEK293,C-His |
F7FZR9/XP_001101108.1(E23-G375) |
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| FGFR-3 regulates chondrocyte differentiation and proliferation by activating the MAPK/STAT signaling pathway. FGFR-3 is a tumor marker. | |||
