补体系统中的一个关键蛋白,参与经典途径激活,形成C3转化酶,在免疫防御和炎症反应中发挥重要作用。
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| 产品号 | 产品名称 | 蛋白编码 | 图片 |
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| ALP6839 | P21180 -1 (A19-L760) |
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| 补体 C2 是补体系统经典途径的一个组成部分,被激活的因子 C1 裂解,导致形成两个不同的片段:C2b 和 C2a。C2a 随后的丝氨酸蛋白酶活性对于其随后与补体因子 C4b 的相互作用至关重要,从而导致 C3 或 C5 转化酶的形成。 | |||
| ALP9278 |
Recombinant Cynomolgus Complement Component C2 Protein,Cynomolgus,C-His,Expi293 重组蛋白Cynomolgus Complement Component C2 Protein,Cynomolgus,C-His,Expi293 |
XP_005553508.1(Ala21-Leu752) |
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| Single nucleotide polymorphism (SNP) of complement component 2 (C2) has been found to be significantly associated with hepatocellular carcinoma (HCC). Significantly lower C2 expression was found at HCC compared to healthy controls, and C2 was associated with TNM stages. Higher C2 expression was significantly associated with better prognosis, and multivariate analysis showed that C2 was also an independent factor for the prognosis of HCC. | |||
| ALP9279 |
Recombinant Human Complement Component C2 Protein,Human,C-His,Expi293 重组蛋白Human Complement Component C2 Protein,Human,C-His,Expi293 |
P06681-1(Ala21-Leu752) |
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| Single nucleotide polymorphism (SNP) of complement component 2 (C2) has been found to be significantly associated with hepatocellular carcinoma (HCC). Significantly lower C2 expression was found at HCC compared to healthy controls, and C2 was associated with TNM stages. Higher C2 expression was significantly associated with better prognosis, and multivariate analysis showed that C2 was also an independent factor for the prognosis of HCC. | |||
| ALP22514 | P06681(A21-L752) |
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| C2/Complement C2 protein is essential in the classical pathway of the complement system . Activated by factor C1, C2 is cleaved into C2b and C2a. As a serine protease, C2a interacts with C4b, generating the C3 or C5 convertase. This crucial process activates and amplifies the complement cascade. | |||