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种属:	Human (1)
表达系统:	HEK293 (1)
标签:	His (1)

产品号	产品名称	蛋白编码
ALP7346	Human Vitronectin Protein, Human, HEK293, C-6His 重组蛋白Human Vitronectin Protein, Human, HEK293, C-6His	P04004/ AAH05046.1 (D20-L478)
ALP7346	玻连蛋白是血清和组织中的多功能细胞粘附因子，与糖胺聚糖和蛋白聚糖相互作用。它充当细胞和基质之间的粘附分子，与特定的整合素结合。
ALP8255	Recombinant Human CD59 Protein,Human,C-hFc,Expi293 重组蛋白Human CD59 Protein,Human,C-hFc,Expi293	P13987-1(Leu26-Asn102)
ALP8255	CD59 regulates complement activation cascade at the final step, inhibiting formation of membrane attack complex (MAC). This protein, being anchored to the cell membrane via glycosyl phosphatidyl inositol (GPI), is expressed ubiquitously on cells which are in contact with body fluids containing components.
ALP8332	Recombinant Human Complement Factor D/CFD Protein,Human,C-hFc,Expi293 重组蛋白Human Complement Factor D/CFD Protein,Human,C-hFc,Expi293	P00746-1(Ile26-Ala253)
ALP8332	Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium.
ALP8331	Recombinant Human Complement Factor D/CFD Protein,Human,C-His,Expi293 重组蛋白Human Complement Factor D/CFD Protein,Human,C-His,Expi293	P00746-1(Ile26-Ala253)
ALP8331	Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium.
ALP9317	Recombinant Cynomolgus CD46 Protein,Cynomolgus,C-His,Expi293 重组蛋白Cynomolgus CD46 Protein,Cynomolgus,C-His,Expi293	A0A2K5WCS2(Cys35-Asp329)
ALP9317	CD46 was discovered in 1986 during a search for novel C3b-binding proteins. CD46 is expressed ubiquitously and functions as a co-factor in the factor I-mediated proteolytic cleavage of C3b and C4b. Its vital role in preventing complement deposition on host tissue is underpinned by the fact that deficiency of CD46 is a predisposing factor for numerous disease conditions arising from complement-mediated 'self-attack'.
ALP9319	Recombinant Human CD46 Protein,Human,C-His,Expi293 重组蛋白Human CD46 Protein,Human,C-His,Expi293	P15529-1(Cys35-Asp343)
ALP9319	CD46 was discovered in 1986 during a search for novel C3b-binding proteins. CD46 is expressed ubiquitously and functions as a co-factor in the factor I-mediated proteolytic cleavage of C3b and C4b. Its vital role in preventing complement deposition on host tissue is underpinned by the fact that deficiency of CD46 is a predisposing factor for numerous disease conditions arising from complement-mediated 'self-attack'.
ALP9320	Recombinant Cynomolgus CD55 Protein,Cynomolgus,C-His,Expi293 重组蛋白Cynomolgus CD55 Protein,Cynomolgus,C-His,Expi293	A0A2K5X1Z6(Asp36-Ser350)
ALP9320	Decay Accelerating Factor (or CD55) is a major regulator of the alternative and classical pathways of complement activation and is expressed on all serum-exposed cells. It is commonly hijacked by invading pathogens, including many enteroviruses and uropathogenic Escherichia coli, to promote cellular attachment prior to infection.
ALP9322	Recombinant Human CD55 Protein,Human,C-His,Expi293 重组蛋白Human CD55 Protein,Human,C-His,Expi293	P08174-1(Asp35-Ser353)
ALP9322	Decay Accelerating Factor (or CD55) is a major regulator of the alternative and classical pathways of complement activation and is expressed on all serum-exposed cells. It is commonly hijacked by invading pathogens, including many enteroviruses and uropathogenic Escherichia coli, to promote cellular attachment prior to infection.
ALP9323	Recombinant Mouse CD55 Protein,Mouse,C-His,Expi293 重组蛋白Mouse CD55 Protein,Mouse,C-His,Expi293	Q61475(Asp35-Gly362)
ALP9323	Decay Accelerating Factor (or CD55) is a major regulator of the alternative and classical pathways of complement activation and is expressed on all serum-exposed cells. It is commonly hijacked by invading pathogens, including many enteroviruses and uropathogenic Escherichia coli, to promote cellular attachment prior to infection.
ALP9361	Recombinant Rhesus macaque Complement Factor D/CFD Protein,Rhesus macaque,C-His,Expi293 重组蛋白Rhesus macaque Complement Factor D/CFD Protein,Rhesus macaque,C-His,Expi293	H9EXC1-1(Gln21-Ala253)
ALP9361	Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium.
ALP9362	Recombinant Human Factor H/CFH Protein,Human,C-His,Expi293 重组蛋白Human Factor H/CFH Protein,Human,C-His,Expi293	P08603-1(Ser860-Arg1231)
ALP9362	Factor H is the major soluble inhibitor of complement, where its binding to self markers (i.e., particular glycan structures) prevents complement activation and amplification on host surfaces. Not surprisingly, mutations and polymorphisms that affect recognition of self by factor H are associated with diseases of complement dysregulation, such as age-related macular degeneration and atypical haemolytic uremic syndrome. In addition, pathogens (i.e., non-self) and cancer cells (i.e., altered-self) can hijack factor H to evade the immune response.
ALP9363	Recombinant Mouse Factor H/CFH Protein,Mouse,C-His,Expi293 重组蛋白Mouse Factor H/CFH Protein,Mouse,C-His,Expi293	NP_034018.2(Ser875-Val1252)
ALP9363	Factor H is the major soluble inhibitor of complement, where its binding to self markers (i.e., particular glycan structures) prevents complement activation and amplification on host surfaces. Not surprisingly, mutations and polymorphisms that affect recognition of self by factor H are associated with diseases of complement dysregulation, such as age-related macular degeneration and atypical haemolytic uremic syndrome. In addition, pathogens (i.e., non-self) and cancer cells (i.e., altered-self) can hijack factor H to evade the immune response.
ALP22650	Recombinant CD55/DAF Protein,Rat,HEK293,C-Fc 重组蛋白CD55/DAF Protein,Rat,HEK293,C-Fc	Q9Z0M0(D35-S371)
ALP22650	The CD55/DAF protein lacks conserved residues critical for feature annotation propagation and exhibits unique qualities that have prompted exploration of its structural and functional implications. This unique property suggests underlying nuances in molecular interactions and regulatory mechanisms.
ALP22513	Recombinant Complement factor H/CFH Protein,Human 372a.a,HEK293,C-His 重组蛋白Complement factor H/CFH Protein,Human 372a.a,HEK293,C-His	P08603-1(S860-R1231)
ALP22513	Complement factor H/CFH proteins regulate complement activation and act as soluble inhibitors to prevent complement amplification on the cell surface.
ALP22515	Recombinant Complement Factor D/Adipsin Protein,Human,HEK293,C-His,Solution 重组蛋白Complement Factor D/Adipsin Protein,Human,HEK293,C-His,Solution	P00746(I26-A253)
ALP22515	Complement factor D , also known as Adipsin, plays a crucial role in the alternative pathway of the complement system and when complexed with factor C3b, it cleaves factor B. This cleavage activates the C3bbb complex, converting it to the C3 convertase of the alternative pathway.
ALP22516	Recombinant CD55/DAF Protein,Human,HEK293,C-hFc 重组蛋白CD55/DAF Protein,Human,HEK293,C-hFc	P08174(D35-S353)
ALP22516	The CD55/DAF protein is critical in the immune system, recognizing C4b and C3b fragments, interfering with their enzymatic conversion and preventing the formation of complement cascade amplifying convertase. This regulatory mechanism alleviates complement-induced damage by inhibiting complement activation.
ALP22521	Recombinant CFHR5 Protein,Human,HEK293,C-His 重组蛋白CFHR5 Protein,Human,HEK293,C-His	Q9BXR6(E19-E569)
ALP22521	CFHR5 is a first-line complement regulator that is actively involved in the complex dynamics of the regulatory system. Dimeric CFHR5 has significant affinity for tissue-bound complement fragments, thereby challenging CFH.
ALP22610	Recombinant Complement Factor B/CFB Protein,Human,HEK293,C-His 重组蛋白Complement Factor B/CFB Protein,Human,HEK293,C-His	AAH04143.1(T26-L764)
ALP22610	Complement Factor B/CFB Protein, Human (HEK293, His) is the recombinant human-derived Complement Factor B/CFB protein, expressed by HEK293 , with C-6*His labeled tag.
ALP22612	Recombinant CFHR3 Protein,Human,HEK293,C-His 重组蛋白CFHR3 Protein,Human,HEK293,C-His	Q02985-1(Q19-E330)
ALP22612	CFHR3 Protein is implicated in regulating the complement system .
ALP22613	Recombinant CFHR4 Protein,Human,HEK293,C-His 重组蛋白CFHR4 Protein,Human,HEK293,C-His	Q92496-1(E20-E578)
ALP22613	CFHR4, a key regulator of complement, intricately orchestrates the complement system . It associates with lipoproteins, suggesting involvement in lipid metabolism. Operating as a homodimer, CFHR4 plays a crucial role in balancing complement activation and regulation.

Complement Regulatory Proteins