一种冠状病毒的蛋白质,包括刺突蛋白、核衣壳蛋白等,负责病毒入侵宿主细胞、复制和组装,是疫苗和药物研发的关键靶点。
| 产品号 | 产品名称 | 蛋白编码 | 图片 |
|---|---|---|---|
| ALP8095 |
Recombinant SARS-Cov-2 Spike RBD (Omicron BA.2.12.1) Protein,SARS-COV-2,C-His,Expi293 重组蛋白SARS-Cov-2 Spike RBD (Omicron BA.2.12.1) Protein,SARS-COV-2,C-His,Expi293 |
QHD43416.1(Arg319-Phe541(G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H)) |
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| B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the activation and regulation of T cell immunity. B7-1 and B7-2 do not form hetero-oligomers, underscoring the biological relevance of dimeric and monomeric state of B7-1 and B7-2, respectively. | |||
| ALP8354 |
Recombinant SARS-COV-2 Spike S1 (Omicron B.1.1.529) Protein,SARS-COV-2,C-His,Expi293 重组蛋白SARS-COV-2 Spike S1 (Omicron B.1.1.529) Protein,SARS-COV-2,C-His,Expi293 |
QHO60594.1(Gln14-Arg683(A67V, HV69-70del, T95I, G142D, VYY143-145del, N211del, L212I, ins214EPE, G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H, T547K, D614G, H655Y, N679K, P681H)) |
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| The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. | |||
| ALP8358 |
Recombinant SARS-COV-2 Spike RBD Protein,SARS-COV-2,C-His-Avi,Expi293 重组蛋白SARS-COV-2 Spike RBD Protein,SARS-COV-2,C-His-Avi,Expi293 |
QHD43416.1(Arg319-Asn532) |
|
| The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. | |||
| ALP8351 |
Recombinant SARS-COV-2 Spike RBD (Omicron B.1.1.529) Protein,SARS-COV-2,C-His,Expi293 重组蛋白SARS-COV-2 Spike RBD (Omicron B.1.1.529) Protein,SARS-COV-2,C-His,Expi293 |
QHO60594.1(Arg319-Phe541(G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H)) |
|
| The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. | |||
| ALP8355 |
Recombinant SARS-COV-2 Spike S1 (N501Y) Protein,SARS-COV-2,C-His,Expi293 重组蛋白SARS-COV-2 Spike S1 (N501Y) Protein,SARS-COV-2,C-His,Expi293 |
YP_009724390.1(Val16-Arg685) |
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| A new variant of SARS-CoV-2 is spreading in the UK and is rapidly becoming a global threat.It is characterised by multiple mutations in the spike protein. Among them, N501Y is of major concern because it involves one of the six key amino acid residues determining a tight interaction of the SARS-CoV-2 receptor-binding domain (RBD) with its cellular receptor angiotensin-converting enzyme 2 (ACE2). | |||
| ALP8356 |
Recombinant SARS-COV-2 Spike RBD Protein,SARS-COV-2,C-hFc,Expi293 |
QHD43416.1(Arg319-Phe541) |
|
| The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. | |||
| ALP8349 |
Recombinant SARS-COV-2 Spike S (Omicron B.1.1.529) Trimer Protein,SARS-COV-2,C-His,Expi293 重组蛋白SARS-COV-2 Spike S (Omicron B.1.1.529) Trimer Protein,SARS-COV-2,C-His,Expi293 |
QHO60594.1(Val16-Pro1213(A67V, HV69-70del, T95I, G142D, VYY143-145del, N211del, L212I, ins214EPE, G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H, T547K, D614G, H655Y, N679K, P681H, N764K, D796Y, N856K, Q954H, N969K, L981F)) |
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| The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. | |||
| ALP8348 |
Recombinant SARS-COV-2 Spike RBD (N501Y) Protein,SARS-COV-2,C-His,Expi293 重组蛋白SARS-COV-2 Spike RBD (N501Y) Protein,SARS-COV-2,C-His,Expi293 |
QHD43416.1(Arg319-Phe541(N501Y)) |
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| The ongoing coronavirus disease 2019 (COVID-19) pandemic has prioritized the development of small-animal models for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The resulting mouse-adapted strain at passage 6 (called MASCp6) showed increased infectivity in mouse lung and led to interstitial pneumonia and inflammatory responses in both young and aged mice after intranasal inoculation. Deep sequencing revealed a panel of adaptive mutations potentially associated with the increased virulence. In particular, the N501Y mutation is located at the receptor binding domain (RBD) of the spike protein. | |||
| ALP8352 |
Recombinant SARS-COV-2 Spike S1 Protein,SARS-COV-2,C-His,Expi293 |
QHO60594.1(Gln14-Arg683) |
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| The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. | |||
| ALP8350 |
Recombinant SARS-COV-2 Spike RBD (N501Y,K417N,E484K) Protein,SARS-COV-2,C-His,Expi293 重组蛋白SARS-COV-2 Spike RBD (N501Y,K417N,E484K) Protein,SARS-COV-2,C-His,Expi293 |
QHD43416.1(Arg319-Phe541(N501Y,K417N,E484K)) |
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| The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. | |||
| ALP8353 |
Recombinant SARS-COV-2 Spike S1 NTD Protein,SARS-COV-2,C-His-Flag,Expi293 重组蛋白SARS-COV-2 Spike S1 NTD Protein,SARS-COV-2,C-His-Flag,Expi293 |
QHD43416.1(Val16-Ser305) |
|
| The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. | |||
| ALP8357 |
Recombinant SARS-COV-2 Spike RBD Protein,SARS-COV-2,C-mFc,Expi293 |
QHD43416.1(Arg319-Asn532) |
|
| The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. | |||
| ALP8360 |
Recombinant SARS-COV-2 Spike S Trimer (D614G) Protein,SARS-COV-2,C-His-Avi,Expi293 重组蛋白SARS-COV-2 Spike S Trimer (D614G) Protein,SARS-COV-2,C-His-Avi,Expi293 |
QHD43416.1(Val16-Glu1188(D614G)) |
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| The SARS-CoV-2 spike (S) protein variant D614G supplanted the ancestral virus worldwide, reaching near fixation in a matter of months. Recently, that D614G was been found more infectious than the ancestral form on human lung cells, colon cells, and on cells rendered permissive by ectopic expression of human ACE2 or of ACE2 orthologs from various mammals, including Chinese rufous horseshoe bat and Malayan pangolin. | |||
| ALP8367 |
Recombinant SARS-COV-2 Spike S1 Protein,SARS-COV-2,C-hFc-Avi,Expi293 重组蛋白SARS-COV-2 Spike S1 Protein,SARS-COV-2,C-hFc-Avi,Expi293 |
QHD43416.1(Gln14-Arg683) |
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| The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. | |||
| ALP8362 |
Recombinant SARS-COV-2 Spike S1 (D614G) Protein,SARS-COV-2,C-His-Avi,Expi293 重组蛋白SARS-COV-2 Spike S1 (D614G) Protein,SARS-COV-2,C-His-Avi,Expi293 |
QHD43416.1(Gln14-Arg683(D614G)) |
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| The SARS-CoV-2 spike (S) protein is the target of vaccine design efforts to end the COVID-19 pandemic. Despite a low mutation rate, isolates with the D614G substitution in the S protein appeared early during the pandemic, and are now the dominant form worldwide. Here, we analyze the D614G mutation in the context of a soluble S ectodomain construct. | |||
| ALP8364 |
Recombinant SARS-COV-2 Spike S Trimer Protein,SARS-COV-2,C-His-Avi,Expi293 重组蛋白SARS-COV-2 Spike S Trimer Protein,SARS-COV-2,C-His-Avi,Expi293 |
QHD43416.1(Val16-Glu1188) |
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| The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. | |||
| ALP9238 |
Recombinant SARS-CoV-2 Spike S1 (Omicron BA.2.12.1) Protein,SARS-COV-2,C-His,Expi293 重组蛋白SARS-CoV-2 Spike S1 (Omicron BA.2.12.1) Protein,SARS-COV-2,C-His,Expi293 |
QHD43416.1(Gln14-Arg683(T19I, L24S, PPA25-27 del, G142D, V213G, G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H, D614G, H655Y, N679K, P681H)) |
|
| The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. | |||
| ALP9239 |
重组蛋白SARS-CoV-2 Spike RBD (Omicron BA.4/BA.5/BA.5.1.3/BA.5.2) Protein,SARS-COV-2,C-His,Expi293 |
QHD43416.1(Arg319-Phe541(G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H)) |
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| The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. | |||
| ALP9244 |
Recombinant SARS-CoV-2 Spike S1 (Omicron BA.4/BA.5/BA.5.2) Protein,SARS-COV-2,C-His,Expi293 重组蛋白SARS-CoV-2 Spike S1 (Omicron BA.4/BA.5/BA.5.2) Protein,SARS-COV-2,C-His,Expi293 |
QHD43416.1(Gln14-Arg683(T19I, L24S, PPA25-27del, HV69-70del, G142D, V213G, G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H, D614G, H655Y, N679K, P681H)) |
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| The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. | |||
| ALP8911 |
Recombinant SARS-COV-2 NSP7&NSP8 Protein,SARS-CoV-2,C-His,E.coli |
YP_009725303.1(NSP7)(Ser1-Gln83)&YP_009725304.1(NSP8)(Ala1-Gln198) |
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| The crystal structure of the metabolite of remdesivir (Monophosphate of GS-441524) and NSP12-NSP8-NSP7 of SARS CoV-2 virus was recently reported. The crystal structures of ADP-Ribose or AMP and NSP3 of SARS CoV-2 virus were also released, recently. The crystal structure of NSP3 of SARS CoV-2 virus as an alternative binding site of AMP or ADP-ribose to treat COVID-19. | |||