丙型肝炎病毒编码的核心蛋白、包膜糖蛋白及非结构蛋白等,参与病毒复制、组装及宿主免疫逃逸,是抗病毒药物研发的关键靶点。
| 产品号 | 产品名称 | 蛋白编码 | 图片 |
|---|---|---|---|
| ALP23077 |
Recombinant Envelope Glycoprotein E1 Protein,HCV,HEK293,N-His |
AAC15725(Y192-I340) |
|
| Envelope Glycoprotein E1 Protein, one of two subunits of the envelope glycoprotein found in the hepatitis C virus, is a type 1 transmembrane protein.It associates with envelope glycoprotein E2 as a noncovalent heterodimer, which mediates virus attachment to the host cell, virion internalization through clathrin-dependent endocytosis and fusion with host membrane.E1/E2 heterodimer binds host apolipoproteins.And it also binds to CD81 and activates the epithelial growth factor receptor ( EGFR ) signaling pathway. | |||