细菌和真菌产生的蛋白质，参与细胞结构、代谢调控及病原体与宿主互作，在生物技术和医学研究中具有重要应用价值。
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| 产品号 | 产品名称 | 蛋白编码 | 图片 |
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| ALP6814 |
Listeria monocytogenes Flagellin Protein, Listeria monocytogenes, E.coli, N-6His 重组蛋白Listeria monocytogenes Flagellin Protein, Listeria monocytogenes, E.coli, N-6His |
WP_003724427.1 (M1-S287) |
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| Flagellin 蛋白是聚合形成细菌鞭毛丝的亚基蛋白。它是一种天然的免疫激动剂，可激活先天免疫，然后刺激适应性免疫反应。鞭毛蛋白通过 TLR5 直接激活许多免疫和非免疫细胞。此外，它还具有抗肿瘤和辐射防护活性，在对抗肿瘤生长和辐射相关的组织损伤方面显示出巨大的潜力。 | |||
| ALP23227 |
Recombinant Hydrophobin-1/HFB1 Protein,Hypocrea jecorina,E. coli,N-His-SUMO 重组蛋白Hydrophobin-1/HFB1 Protein,Hypocrea jecorina,E. coli,N-His-SUMO |
P52754(S23-A97) |
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| The Hydrophobin-1/HFB1 protein plays a crucial role in enhancing surface hydrophobicity, which is an important factor in a variety of biological processes, including hyphal binding in reproductive structures, dispersal of aerial spores, and effects on the host Pathogenic responses to structural adhesion. | |||
| ALP23019 |
Recombinant Enterotoxin type B Protein,S. aureus,P.pastoris,N-His |
P01552(E28-K266) |
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| Enterotoxin B (SEB) is an antigen derived from Staphylococcus aureus ( S. aureus ) that can be recognized and bound by MHC class II molecules on antigen-presenting cells. Enterotoxin B also interacts with T cell receptors (TCRs), triggering massive activation of CD4+ and CD8+ T cells, leading to the release of proinflammatory cytokines (TNF-α, IFN-γ ) and Th2-type cytokines ( IL-4 , IL-5 , IL-13 ), regulating inflammatory responses. Enterotoxin B also exerts anti-tumor potential in fibrosarcoma models, inducing tumor necrosis. | |||
| ALP23020 |
Recombinant Enterotoxin type A Protein,S. aureus,E. coli,N-His |
P0A0L2(S25-S257) |
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| Enterotoxins (ETAs) trigger host immune system activation by binding to major histocompatibility complex class II and T-cell receptor (TCR) molecules. This interaction triggers a cascade of cell activation, cytokine production and migration, primarily mediated by Alphata T cells, affecting lung tissue and airways. | |||
| ALP23021 |
Recombinant Enterotoxin type E Protein,S. aureus,E. coli,N-His |
P12993(S28-T257) |
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| ENTE Proteinas are staphylococcal enterotoxins that activate the host immune system by binding to major histocompatibility complex class II and T-cell receptor (TCR) molecules. This interaction forms a ternary complex that activates T lymphocytes and induces the systemic release of proinflammatory cytokines. | |||
| ALP23052 |
Recombinant Clumping factor B Protein,S. aureus,E. coli,His,N-SUMO |
Q6GDH2(S45-N542) |
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| Clumping factor B (ClfB) is a cell surface-associated protein implicated in virulence, playing a crucial role in bacterial pathogenicity by promoting bacterial attachment to both alpha- and beta-chains of human fibrinogen. Its significance lies in inducing the formation of bacterial clumps, a mechanism that contributes to the pathogenicity and virulence of the bacteria. | |||
| ALP23053 |
Recombinant Clumping factor A Protein,S. aureus,E. coli,Tag Free |
Q6GB45(G228-E558) |
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| Clustering factor A (ClfA) is a virulence-related cell surface-associated protein that plays a key role in bacterial pathogenicity. It promotes bacterial attachment exclusively to the gamma chain of human fibrinogen, demonstrating the specificity of its interaction with host proteins. | |||
| ALP23057 | P08191(F22-Q300) |
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| FimH Protein, pivotal in regulating length, mediates adhesion for type 1 fimbriae without being essential for fimbriae production. Positioned laterally in the fimbriae structure, FimH primarily binds to D-mannose. FimH integration into fimbriae involves collaborative action with FimF and FimG, emphasizing the coordinated molecular interplay essential for type 1 fimbriae assembly and function. | |||
| ALP23081 |
Recombinant Enterotoxin type E Protein,S. aureus,HEK293,His,N-Myc |
P12993(S28-T257) |
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| ENTE Proteinas are staphylococcal enterotoxins that activate the host immune system by binding to major histocompatibility complex class II and T-cell receptor (TCR) molecules. This interaction forms a ternary complex that activates T lymphocytes and induces the systemic release of proinflammatory cytokines. | |||
| ALP23087 |
Recombinant Exfoliative toxin A Protein,S. aureus,E. coli,N-His |
P09331(E39-E280) |
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| Exfoliative toxin A protein, with serine protease-like properties, binds to skin protein profilaggrin, demonstrating cleavage activity after acidic residues. Its involvement is associated with impetigous diseases, particularly staphylococcal scalded skin syndrome (SSSS). | |||
| ALP23131 | Q46669(D19-R269) |
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| CDTB Protein, integral to the tripartite complex for Cytolethal Distending Toxin (CDT) activity, features DNA-nicking endonuclease action, likely causing DNA damage. This damage prompts G2/M cell cycle arrest, chromatin fragmentation, cell distention, and nucleus enlargement. Collaborating with CdtA and CdtC, CDTB forms a crucial unit for CDT's cytotoxic effects, showcasing its multifaceted role in cellular responses to CDT intoxication. | |||
| ALP23129 | P0A9A7(M1-D383) |
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| FtsZ is an essential cell division protein that plays a central role in coordinating the formation of the contractile Z ring at the site of expected cell division. Precise regulation of the components of this ring is a key determinant, affecting the timing and location of cell division. | |||
